Seidensticker Florian, Neubauer Aljoscha S, Wasfy Tamer, Stumpf Carmen, Thurau Stephan R, Kampik Anselm, Kernt Marcus
Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Clin Ophthalmol. 2011;5:1667-71. doi: 10.2147/OPTH.S26224. Epub 2011 Nov 29.
Detection of peripheral fundus autofluorescence (FAF) using conventional scanning laser ophthalmoscopes (SLOs) is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.
STUDY DESIGN/MATERIALS AND METHODS: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.
Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.
Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.
使用传统扫描激光检眼镜(SLO)检测周边眼底自发荧光(FAF)较为困难,且需要散瞳。在此,我们评估了双激光波长宽视野SLO检测的宽视野FAF在葡萄膜炎患者中的诊断特性。
研究设计/材料与方法:对4例患有不同类型后葡萄膜炎/脉络膜视网膜炎的患者进行观察性病例系列研究。将宽视野FAF图像与视野进行比较。通过新开发的SLO检测全视网膜FAF图像,该设备可在一次扫描中对视网膜200°范围进行FAF成像,无需散瞳。视野通过戈德曼手动视野计获得。
宽视野FAF成像结果在所有病例中均显示与视野缺损相符。
宽视野FAF能够在所有4例葡萄膜炎病例中检测到与视野缺损相关的视网膜色素上皮改变。