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广角眼底自发荧光与脉络膜视网膜炎患者的视野相对应。

Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients.

作者信息

Seidensticker Florian, Neubauer Aljoscha S, Wasfy Tamer, Stumpf Carmen, Thurau Stephan R, Kampik Anselm, Kernt Marcus

机构信息

Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.

出版信息

Clin Ophthalmol. 2011;5:1667-71. doi: 10.2147/OPTH.S26224. Epub 2011 Nov 29.

Abstract

BACKGROUND AND OBJECTIVES

Detection of peripheral fundus autofluorescence (FAF) using conventional scanning laser ophthalmoscopes (SLOs) is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.

STUDY DESIGN/MATERIALS AND METHODS: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.

RESULTS

Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.

CONCLUSION

Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.

摘要

背景与目的

使用传统扫描激光检眼镜(SLO)检测周边眼底自发荧光(FAF)较为困难,且需要散瞳。在此,我们评估了双激光波长宽视野SLO检测的宽视野FAF在葡萄膜炎患者中的诊断特性。

研究设计/材料与方法:对4例患有不同类型后葡萄膜炎/脉络膜视网膜炎的患者进行观察性病例系列研究。将宽视野FAF图像与视野进行比较。通过新开发的SLO检测全视网膜FAF图像,该设备可在一次扫描中对视网膜200°范围进行FAF成像,无需散瞳。视野通过戈德曼手动视野计获得。

结果

宽视野FAF成像结果在所有病例中均显示与视野缺损相符。

结论

宽视野FAF能够在所有4例葡萄膜炎病例中检测到与视野缺损相关的视网膜色素上皮改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b482/3236712/709767104a8d/opth-5-1667f1.jpg

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