[赖氨酸（24、38、83）]人促红细胞生成素的汇聚化学合成 - Suppr

Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.

作者信息

Liu Suhuai, Pentelute Brad L, Kent Stephen B H

机构信息

Department of Biochemistry and Molecular Biology, Gordon Center for Integrative Science, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

出版信息

Angew Chem Int Ed Engl. 2012 Jan 23;51(4):993-9. doi: 10.1002/anie.201106060. Epub 2011 Dec 16.

DOI:10.1002/anie.201106060

PMID:22180156

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3472960/

Abstract

摘要

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Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.

作者信息

Liu Suhuai, Pentelute Brad L, Kent Stephen B H

机构信息

Department of Biochemistry and Molecular Biology, Gordon Center for Integrative Science, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

出版信息

Angew Chem Int Ed Engl. 2012 Jan 23;51(4):993-9. doi: 10.1002/anie.201106060. Epub 2011 Dec 16.

DOI:10.1002/anie.201106060

PMID:22180156

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3472960/

Abstract

摘要

相似文献

Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.

Angew Chem Int Ed Engl. 2012 Jan 23;51(4):993-9. doi: 10.1002/anie.201106060. Epub 2011 Dec 16.

Chemical protein synthesis: Inventing synthetic methods to decipher how proteins work.

Bioorg Med Chem. 2017 Sep 15;25(18):4926-4937. doi: 10.1016/j.bmc.2017.06.020. Epub 2017 Jun 15.

At last: erythropoietin as a single glycoform.

Angew Chem Int Ed Engl. 2012 Nov 12;51(46):11576-84. doi: 10.1002/anie.201206090. Epub 2012 Sep 25.

Chemical synthesis of an erythropoietin glycoform containing a complex-type disialyloligosaccharide.

Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3567-72. doi: 10.1002/anie.201109034. Epub 2012 Feb 3.

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Proc Natl Acad Sci U S A. 2012 May 8;109(19):7196-201. doi: 10.1073/pnas.1202762109. Epub 2012 Apr 12.

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Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9558-62. doi: 10.1002/anie.201302197. Epub 2013 Jun 26.

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J Org Chem. 2016 Dec 2;81(23):11612-11625. doi: 10.1021/acs.joc.6b01829. Epub 2016 Nov 8.

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Chem Biol. 2001 Feb;8(2):133-45. doi: 10.1016/s1074-5521(00)90065-6.

Synthesis and semisynthesis of selenopeptides and selenoproteins.

Curr Opin Chem Biol. 2018 Oct;46:41-47. doi: 10.1016/j.cbpa.2018.04.008. Epub 2018 Apr 30.

Hmb(off/on) as a switchable thiol protecting group for native chemical ligation.

Org Biomol Chem. 2016 May 4;14(18):4194-8. doi: 10.1039/c6ob00450d.

引用本文的文献

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Molecules. 2025 Jun 3;30(11):2444. doi: 10.3390/molecules30112444.

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J Pept Sci. 2025 May;31(5):e70013. doi: 10.1002/psc.70013.

Chemical Protein Engineering: Backbone Cyclization Rescues Folding of a 183-Residue Truncated Domain of Malaria Parasite Protein PfAMA1.

Chemistry. 2025 May 19;31(28):e202500894. doi: 10.1002/chem.202500894. Epub 2025 Apr 21.

One-Pot Total Synthesis of a Post-translationally Modified Max Transcription Factor Sheds Light on Ser-Phosphorylation and Lys-Acetylation Crosstalk in DNA Binding.

Org Lett. 2025 Apr 11;27(14):3760-3764. doi: 10.1021/acs.orglett.5c00978. Epub 2025 Mar 31.

Chemical Synthesis Reveals Pathogenic Role of -Glycosylation in Microtubule-Associated Protein Tau.

J Am Chem Soc. 2025 Feb 26;147(8):6995-7007. doi: 10.1021/jacs.4c17873. Epub 2025 Feb 17.

Post-Translational Modifications Control Phase Transitions of Tau.

ACS Cent Sci. 2024 Nov 13;10(11):2145-2161. doi: 10.1021/acscentsci.4c01319. eCollection 2024 Nov 27.

Noncanonical Amino Acids in Biocatalysis.

Chem Rev. 2024 Jul 24;124(14):8740-8786. doi: 10.1021/acs.chemrev.4c00120. Epub 2024 Jul 3.

Post-Translational Modifications Control Phase Transitions of Tau.

bioRxiv. 2024 Mar 12:2024.03.08.583040. doi: 10.1101/2024.03.08.583040.

Chemoenzymatic Semisynthesis of Proteins.

Chem Rev. 2020 Mar 25;120(6):3051-3126. doi: 10.1021/acs.chemrev.9b00450. Epub 2019 Nov 27.

A synthetic approach to 'click' neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry.

Chem Sci. 2018 Oct 29;10(3):815-828. doi: 10.1039/c8sc03409e. eCollection 2019 Jan 21.

本文引用的文献

Total chemical synthesis of biologically active vascular endothelial growth factor.

Angew Chem Int Ed Engl. 2011 Aug 22;50(35):8029-33. doi: 10.1002/anie.201103237. Epub 2011 Jul 8.

Chemical synthesis of homogeneous glycopeptides and glycoproteins.

Chem Rec. 2010 Apr;10(2):80-100. doi: 10.1002/tcr.200900024.

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Tetrahedron. 2009 Nov 7;65(45):9047-9065. doi: 10.1016/j.tet.2009.09.032.

Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods.

Angew Chem Int Ed Engl. 2009;48(50):9557-60. doi: 10.1002/anie.200904376.

Total chemical synthesis of proteins.

Chem Soc Rev. 2009 Feb;38(2):338-51. doi: 10.1039/b700141j. Epub 2008 Sep 16.

Erythropoietin, the first century.

Leuk Res. 2008 Aug;32(8):1169-72. doi: 10.1016/j.leukres.2008.01.018. Epub 2008 Mar 12.

Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides.

Angew Chem Int Ed Engl. 2007;46(48):9248-52. doi: 10.1002/anie.200704195.

Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule.

Angew Chem Int Ed Engl. 2007;46(10):1667-70. doi: 10.1002/anie.200604087.

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Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4846-51. doi: 10.1073/pnas.0610630104. Epub 2007 Mar 8.

Selective desulfurization of cysteine in the presence of Cys(Acm) in polypeptides obtained by native chemical ligation.

Org Lett. 2007 Feb 15;9(4):687-90. doi: 10.1021/ol0630144.

Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.

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Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.

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