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通过唾液和头发中的皮质醇反应测量短期和长期生理应激效应。

Measuring short-term and long-term physiological stress effects by cortisol reactivity in saliva and hair.

机构信息

Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE, Amsterdam, The Netherlands.

出版信息

Int Arch Occup Environ Health. 2012 Nov;85(8):849-52. doi: 10.1007/s00420-011-0727-3. Epub 2011 Dec 20.

DOI:10.1007/s00420-011-0727-3
PMID:22183048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3480579/
Abstract

PURPOSE

The aims of this study were to investigate (1) the concurrent relationship between short-term and long-term stress reactivity measured by cortisol excretion and (2) the relationship of these physiological stress effects with self-reported stress and need for recovery after work (NFR).

METHODS

Participants were production workers in the meat-processing industry. Short-term cortisol excretion was calculated by summing 18 saliva samples, sampled over a 3-day period. Samples were delivered by 37 participants. Twenty-nine of them also supplied one hair sample of at least 3 cm in length for an analysis of long-term (3 months) cortisol excretion. All of them filled in a short questionnaire on self-reported stress and NFR. Self-reported stress was assessed by a three-item stress screener; NFR was assessed by an 11-item scale.

RESULTS

Short-term and long-term cortisol excretion are significantly, but moderately, associated (r = 0.41, P = 0.03). Short-term and long-term cortisol excretion correlated weakly to self-reported stress and NFR (correlations varied from -0.04 to 0.21).

CONCLUSIONS

Short-term and long-term physiological stress excretion levels are moderately associated. Physiological stress effects assessed from saliva and hair cannot be used interchangeably with self-reported stress because they only correlate weakly. To better predict long-term cortisol excretion in workers, the predictive value of short-term cortisol excretion must be evaluated in a prognostic longitudinal study in a working population.

摘要

目的

本研究旨在探究(1)通过皮质醇排泄测量的短期和长期应激反应之间的并发关系,以及(2)这些生理应激效应与自我报告的应激和工作后恢复需求(NFR)之间的关系。

方法

参与者为肉类加工行业的生产工人。短期皮质醇排泄通过对 3 天内采集的 18 个唾液样本进行求和计算得出。有 37 名参与者提供了样本。其中 29 名参与者还提供了至少 3 厘米长的头发样本,用于分析 3 个月的长期皮质醇排泄。他们所有人都填写了一份关于自我报告的应激和 NFR 的简短问卷。自我报告的应激通过一个三项目的应激筛查器进行评估;NFR 通过一个 11 项的量表进行评估。

结果

短期和长期皮质醇排泄呈显著但适度的相关性(r=0.41,P=0.03)。短期和长期皮质醇排泄与自我报告的应激和 NFR 呈弱相关(相关性从-0.04 到 0.21 不等)。

结论

短期和长期生理应激排泄水平中度相关。从唾液和头发评估的生理应激效应不能与自我报告的应激互换使用,因为它们只有弱相关。为了更好地预测工人的长期皮质醇排泄,必须在工作人群中进行预后性纵向研究来评估短期皮质醇排泄的预测价值。

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