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用自适应光学技术对光感受器嵌合体进行成像:超越锥体细胞计数。

Imaging the photoreceptor mosaic with adaptive optics: beyond counting cones.

机构信息

Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

出版信息

Adv Exp Med Biol. 2012;723:451-8. doi: 10.1007/978-1-4614-0631-0_57.

DOI:10.1007/978-1-4614-0631-0_57
PMID:22183364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3325514/
Abstract

Recent years have seen an explosion in the development of novel ophthalmic imaging devices, delivering non-invasive views of the living retina. Adaptive optics (AO) imaging systems enable resolution of individual cells in the living retina. Analysis of these images has been limited to measures of cone density and regularity. Here we introduce a small case series where the information in the high-resolution image extends beyond these standard metrics. These images should serve as the basis for evolving discussion as to how best to interpret AO retinal images.

摘要

近年来,新型眼科成像设备的发展突飞猛进,为活体视网膜提供了非侵入性的视图。自适应光学(AO)成像系统能够解析活体视网膜中的单个细胞。对这些图像的分析仅限于对锥体密度和规则性的测量。在这里,我们介绍了一个小案例系列,其中高分辨率图像中的信息超出了这些标准指标。这些图像应该为如何最好地解释 AO 视网膜图像的讨论提供基础。

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本文引用的文献

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Quantitative comparison of drusen segmented on SD-OCT versus drusen delineated on color fundus photographs.在频域光学相干断层扫描(SD-OCT)上分割出的玻璃膜疣与在彩色眼底照片上描绘出的玻璃膜疣的定量比较。
Invest Ophthalmol Vis Sci. 2010 Oct;51(10):4875-83. doi: 10.1167/iovs.09-4962. Epub 2010 Apr 14.
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Imaging outer segment renewal in living human cone photoreceptors.活体人类视锥光感受器中外段更新的成像
Opt Express. 2010 Mar 1;18(5):5257-70. doi: 10.1364/OE.18.005257.
3
Advances in imaging of Stargardt disease.Stargardt 病的影像学进展。
Adv Exp Med Biol. 2010;664:333-40. doi: 10.1007/978-1-4419-1399-9_38.
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Arrested development: high-resolution imaging of foveal morphology in albinism.发育停滞:白化病中黄斑形态的高分辨率成像
Vision Res. 2010 Apr 7;50(8):810-7. doi: 10.1016/j.visres.2010.02.003. Epub 2010 Feb 10.
5
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Arch Ophthalmol. 2010 Feb;128(2):253-4. doi: 10.1001/archophthalmol.2009.383.
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The relationship between visual resolution and cone spacing in the human fovea.人眼中央凹处的视觉分辨率与视锥细胞间距的关系。
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