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ECT 和 MST 在治疗抑郁症中的应用。

The use of ECT and MST in treating depression.

机构信息

Department of Psychiatry, University of Oxford, Oxford, UK.

出版信息

Int Rev Psychiatry. 2011 Oct;23(5):400-12. doi: 10.3109/09540261.2011.614223.

DOI:10.3109/09540261.2011.614223
PMID:22200130
Abstract

Electroconvulsive therapy (ECT) has been used clinically since 1938. Its most common use is in the treatment of depression: first line treatment where rapid recovery is a priority, but more frequently as an effective treatment for patients who do not respond to pharmacological and psychological approaches. Whilst it is widely hailed as an effective treatment, concerns about its effect on cognition remain. The development of magnetic seizure therapy (MST) over the past decade has attempted to devise a therapy with comparable efficacy to ECT, but without the associated cognitive side effects. The rationale for this is that MST uses magnetic fields to induce seizures in the cortex, without electrical stimulation of brain structures involved with memory. MST has been used successfully in the treatment of depression, yet there is a dearth of literature in comparison with ECT. We present a systematic review of the literature on ECT (from 2009-2011) and MST (from 2001-2011).

摘要

电抽搐治疗(ECT)自 1938 年以来一直用于临床。它最常见的用途是治疗抑郁症:作为快速康复的首选一线治疗方法,但更常用于对药物和心理治疗方法没有反应的患者的有效治疗方法。尽管它被广泛认为是一种有效的治疗方法,但人们仍然对其对认知的影响表示关注。过去十年中,磁惊厥治疗(MST)的发展试图设计出一种与 ECT 疗效相当但没有相关认知副作用的治疗方法。其基本原理是 MST 使用磁场在皮层中引发癫痫发作,而无需对与记忆相关的脑结构进行电刺激。MST 已成功用于治疗抑郁症,但与 ECT 相比,文献资料匮乏。我们对 ECT(2009-2011 年)和 MST(2001-2011 年)的文献进行了系统评价。

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Cellular and Molecular Effects of Magnetic Fields.磁场的细胞和分子效应。
Int J Mol Sci. 2024 Aug 17;25(16):8973. doi: 10.3390/ijms25168973.
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Magnetic seizure therapy for people with schizophrenia.磁惊厥治疗精神分裂症。
Cochrane Database Syst Rev. 2023 Jun 5;6(6):CD012697. doi: 10.1002/14651858.CD012697.pub2.
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Magnetic seizure therapy.磁休克疗法
Ind Psychiatry J. 2021 Oct;30(Suppl 1):S320-S321. doi: 10.4103/0972-6748.328841. Epub 2021 Oct 22.
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Vagus Nerve Stimulation (VNS) and Other Augmentation Strategies for Therapy-Resistant Depression (TRD): Review of the Evidence and Clinical Advice for Use.迷走神经刺激(VNS)及其他针对难治性抑郁症(TRD)的强化治疗策略:证据综述与临床应用建议
Front Neurosci. 2018 Apr 10;12:239. doi: 10.3389/fnins.2018.00239. eCollection 2018.
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