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磁场的细胞和分子效应。

Cellular and Molecular Effects of Magnetic Fields.

机构信息

Student Research Group № K148, Faculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.

Student Research Group № K148, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.

出版信息

Int J Mol Sci. 2024 Aug 17;25(16):8973. doi: 10.3390/ijms25168973.

Abstract

Recently, magnetic fields (MFs) have received major attention due to their potential therapeutic applications and biological effects. This review provides a comprehensive analysis of the cellular and molecular impacts of MFs, with a focus on both in vitro and in vivo studies. We investigate the mechanisms by which MFs influence cell behavior, including modifications in gene expression, protein synthesis, and cellular signaling pathways. The interaction of MFs with cellular components such as ion channels, membranes, and the cytoskeleton is analyzed, along with their effects on cellular processes like proliferation, differentiation, and apoptosis. Molecular insights are offered into how MFs modulate oxidative stress and inflammatory responses, which are pivotal in various pathological conditions. Furthermore, we explore the therapeutic potential of MFs in regenerative medicine, cancer treatment, and neurodegenerative diseases. By synthesizing current findings, this article aims to elucidate the complex bioeffects of MFs, thereby facilitating their optimized application in medical and biotechnological fields.

摘要

最近,磁场(MFs)因其潜在的治疗应用和生物学效应而受到广泛关注。本综述对磁场的细胞和分子影响进行了全面分析,重点关注了体外和体内研究。我们研究了磁场影响细胞行为的机制,包括基因表达、蛋白质合成和细胞信号通路的改变。分析了磁场与离子通道、膜和细胞骨架等细胞成分的相互作用,以及它们对细胞过程(如增殖、分化和凋亡)的影响。提供了磁场如何调节氧化应激和炎症反应的分子见解,这些反应在各种病理条件中至关重要。此外,我们还探讨了磁场在再生医学、癌症治疗和神经退行性疾病中的治疗潜力。通过综合当前的研究结果,本文旨在阐明磁场的复杂生物效应,从而促进其在医学和生物技术领域的优化应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b63f/11354277/ffc3684659f2/ijms-25-08973-g001.jpg

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