Chee C K, Flanagan D W
Department of Ophthalmology, Addenbrooke's Hospital, Cambridge.
Br J Ophthalmol. 1993 Nov;77(11):726-30. doi: 10.1136/bjo.77.11.726.
Thirty two eyes of 19 patients with capillary non-perfusion from preproliferative and early proliferative diabetic retinopathy underwent visual field testing on the 30-2 program of the Humphrey visual field analyser. The mean defect (MD) p value was < 5% in 30 (94%) eyes and the corrected pattern standard deviation (CPSD) was < 10% in 31 (97%) eyes. Areas of capillary non-perfusion demonstrated by fundal fluorescein angiography were closely associated with areas of reduced retinal sensitivity in these 31 eyes. More severe visual field defects were present in non-insulin dependent diabetics and in older patients. MD and CPSD p values of less than 0.5% and 1% respectively were found to be associated with non-insulin dependent diabetes (p < 0.05 and p < 0.01 respectively) and with the older age group (p < 0.05). There was no correlation between severity of field defects with hypertension and degree of retinopathy.
19例患有增殖前期和早期增殖性糖尿病视网膜病变且存在毛细血管无灌注的患者的32只眼睛，使用Humphrey视野分析仪的30 - 2程序进行了视野测试。30只（94%）眼睛的平均缺损（MD）p值<5%，31只（97%）眼睛的校正模式标准差（CPSD）<10%。在这31只眼睛中，眼底荧光血管造影显示的毛细血管无灌注区域与视网膜敏感度降低的区域密切相关。非胰岛素依赖型糖尿病患者和老年患者存在更严重的视野缺损。发现MD和CPSD的p值分别小于0.5%和1%与非胰岛素依赖型糖尿病（分别为p<0.05和p<0.01）以及老年组（p<0.05）相关。视野缺损的严重程度与高血压和视网膜病变程度之间没有相关性。
