Joffe Ari R, Carcillo Joe, Anton Natalie, deCaen Allan, Han Yong Y, Bell Michael J, Maffei Frank A, Sullivan John, Thomas James, Garcia-Guerra Gonzalo
Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton Clinic Health Academy 11405-87 Avenue, Edmonton, Alberta, T6G 1C9, Canada.
Philos Ethics Humanit Med. 2011 Dec 29;6:17. doi: 10.1186/1747-5341-6-17.
Many believe that the ethical problems of donation after cardiocirculatory death (DCD) have been "worked out" and that it is unclear why DCD should be resisted. In this paper we will argue that DCD donors may not yet be dead, and therefore that organ donation during DCD may violate the dead donor rule. We first present a description of the process of DCD and the standard ethical rationale for the practice. We then present our concerns with DCD, including the following: irreversibility of absent circulation has not occurred and the many attempts to claim it has have all failed; conflicts of interest at all steps in the DCD process, including the decision to withdraw life support before DCD, are simply unavoidable; potentially harmful premortem interventions to preserve organ utility are not justifiable, even with the help of the principle of double effect; claims that DCD conforms with the intent of the law and current accepted medical standards are misleading and inaccurate; and consensus statements by respected medical groups do not change these arguments due to their low quality including being plagued by conflict of interest. Moreover, some arguments in favor of DCD, while likely true, are "straw-man arguments," such as the great benefit of organ donation. The truth is that honesty and trustworthiness require that we face these problems instead of avoiding them. We believe that DCD is not ethically allowable because it abandons the dead donor rule, has unavoidable conflicts of interests, and implements premortem interventions which can hasten death. These important points have not been, but need to be fully disclosed to the public and incorporated into fully informed consent. These are tall orders, and require open public debate. Until this debate occurs, we call for a moratorium on the practice of DCD.
许多人认为,心脏循环死亡后捐赠(DCD)的伦理问题已经“解决”,不清楚为何要抵制DCD。在本文中,我们将论证DCD捐赠者可能尚未死亡,因此DCD期间的器官捐赠可能违反死亡捐赠者规则。我们首先描述DCD的过程以及该做法的标准伦理依据。然后,我们提出对DCD的担忧,包括以下几点:循环停止的不可逆性尚未发生,且许多声称已经发生的尝试均告失败;DCD过程中各个环节都存在利益冲突,包括在DCD之前决定撤除生命支持,这些冲突根本无法避免;为了保持器官可用性而进行的潜在有害的生前干预即使借助双重效应原则也不合理;声称DCD符合法律意图和当前公认的医学标准具有误导性且不准确;受人尊敬的医学团体的共识声明由于质量低下,包括受利益冲突困扰,并未改变这些论点。此外,一些支持DCD的论点,虽然可能正确,但属于“稻草人论点”,比如器官捐赠的巨大益处。事实是,诚实和守信要求我们面对这些问题而非回避。我们认为DCD在伦理上是不允许的,因为它违背了死亡捐赠者规则,存在不可避免的利益冲突,并且实施了可能加速死亡的生前干预。这些要点尚未向公众充分披露,但需要充分披露并纳入充分知情同意之中。这些要求很高,需要公开的公众辩论。在这场辩论发生之前,我们呼吁暂停DCD的做法。