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乳球菌 garvieae BCC 43578 产生的新型 II 类细菌素 Garvieacin Q

Garvieacin Q, a novel class II bacteriocin from Lactococcus garvieae BCC 43578.

机构信息

National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Thailand.

出版信息

Appl Environ Microbiol. 2012 Mar;78(5):1619-23. doi: 10.1128/AEM.06891-11. Epub 2011 Dec 30.

DOI:10.1128/AEM.06891-11
PMID:22210221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3294492/
Abstract

Lactococcus garvieae BCC 43578 produces a novel class II bacteriocin, garvieacin Q (GarQ), 70 amino acids in length and containing a 20-amino-acid N-terminal leader peptide. It is cleaved at the Gly-Gly site to generate the mature GarQ (5,339 Da), which is especially inhibitory against Listeria monocytogenes ATCC 19115 and other L. garvieae strains.

摘要

加氏乳球菌 BCC 43578 产生一种新型 II 类细菌素，加氏菌素 Q（GarQ），长度为 70 个氨基酸，含有 20 个氨基酸的 N 端前导肽。它在 Gly-Gly 位点被切割，生成成熟的 GarQ（5339 Da），对单核细胞增生李斯特菌 ATCC 19115 和其他加氏乳球菌菌株具有特别的抑制作用。

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