Department of Ophthalmology, Training and Research Hospital, Kayseri, Turkey.
Eye Contact Lens. 2012 May;38(3):142-5. doi: 10.1097/ICL.0b013e318243e7d2.
The aim was to assess corneal endothelial characteristics and central corneal thickness (CCT) in a population of Turkish cataract patients and to define the impact of age and gender on these parameters.
Five hundred and seventeen cataract patients were examined with noncontact specular microscope preoperatively. The eye planned to be operated was selected for analysis. The parameters measured were endothelial cell density (ECD), cell area (CA), coefficient of variation (CV) of the CA, percentage of hexagonal cells (PHCs), and CCT.
The mean values in ECD, CA, CV, PHC, and CCT in all eyes were 2,258 ± 474 cells per square millimeter, 468 ± 130 μm(2), 39%±7%, 49%±12%, and 500 ± 37 μm, respectively. Regression analysis revealed a statistically significant decrease in ECD (R=-0.169, P<0.0001), increase in CA (R=0.186, P<0.0001), and decrease in the CCT (R=-0.122, P=0.006) with increase in age. The changes in the CV (R=0.008, P=0.861) and PHC (R=-0,060, P=0.177) were not found to be dependent on age. The parameters showed no sex differences. The number of eyes with ECD below 1,000 and 2,000 cells per square millimeter was 5 (0.97%) and 130 (25.1%), respectively.
The data from our study emphasize that age, but not gender, is the main determinant of ECD.
评估土耳其白内障患者的角膜内皮特征和中央角膜厚度（CCT），并确定年龄和性别对这些参数的影响。
术前使用非接触式共焦显微镜检查了 517 例白内障患者。选择计划手术的眼睛进行分析。测量的参数包括内皮细胞密度（ECD）、细胞面积（CA）、CA 的变异系数（CV）、六边形细胞百分比（PHC）和 CCT。
所有眼睛的 ECD、CA、CV、PHC 和 CCT 的平均值分别为 2258±474 个细胞/平方毫米、468±130μm²、39%±7%、49%±12%和 500±37μm。回归分析显示，ECD（R=-0.169，P<0.0001）、CA（R=0.186，P<0.0001）和 CCT（R=-0.122，P=0.006）随年龄增加而呈统计学显著下降，CV（R=0.008，P=0.861）和 PHC（R=-0.060，P=0.177）的变化与年龄无关。这些参数没有性别差异。ECD 低于 1000 和 2000 个细胞/平方毫米的眼睛数量分别为 5（0.97%）和 130（25.1%）。
我们研究的数据强调，年龄是 ECD 的主要决定因素，而不是性别。
