Li Yingmei, Fu Zhentao, Liu Jian, Li Miao, Zhang Yuguang, Wu Xinyi
Department of Ophthalmology, The Second People's Hospital of Jinan, No. 148 Jingyi Road, Jinan, Shandong 250001, China.
Academy of Preventive Medicine, Shandong University, Jinan, China.
J Ophthalmol. 2017;2017:9154626. doi: 10.1155/2017/9154626. Epub 2017 May 25.
To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI).
1551 eyes were examined preoperatively. The parameters measured were endothelial cell density (CD), average cell area (CA), coefficient of variation (CV), cell hexagonality (HEX), central corneal thickness (CCT), intraocular pressure (IOP), and axial length (AL).
There were significant differences in CV and BMI between genders. There was a significant decrease in CD, CCT, and IOP and, conversely, an increase in CA and BMI with increasing age. The patients who suffered from hypertension had bigger CA, less CD, and lower HEX than the patients who did not suffer from hypertension. CD has a negative correlation with age and CV and a positive correlation with CCT, CCT has a positive association with CD and IOP, and IOP had a negative relationship with age and a positive relationship with CCT, CA, and HEX.
Normative data for the corneal endothelium, central corneal thickness, and intraocular pressure in the normal age-related cataract patients are reported which will serve as a baseline for comparative studies about cataract.
描述中国年龄相关性白内障患者群体的角膜内皮特征、中央角膜厚度和眼压，并确定年龄、性别、高血压和体重指数（BMI）的影响。
对1551只眼睛进行术前检查。测量的参数包括内皮细胞密度（CD）、平均细胞面积（CA）、变异系数（CV）、细胞六边形性（HEX）、中央角膜厚度（CCT）、眼压（IOP）和眼轴长度（AL）。
性别之间CV和BMI存在显著差异。随着年龄增长，CD、CCT和IOP显著降低，相反，CA和BMI增加。患有高血压的患者比未患高血压的患者CA更大、CD更低、HEX更低。CD与年龄和CV呈负相关，与CCT呈正相关，CCT与CD和IOP呈正相关，IOP与年龄呈负相关，与CCT、CA和HEX呈正相关。
报告了正常年龄相关性白内障患者角膜内皮、中央角膜厚度和眼压的标准数据，这些数据将作为白内障比较研究的基线。
