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本文引用的文献

1
The crystal structure and mechanism of an unusual oxidoreductase, GilR, involved in gilvocarcin V biosynthesis.一种参与吉尔菌素 V 生物合成的不寻常氧化还原酶 GilR 的晶体结构和机制。
J Biol Chem. 2011 Jul 1;286(26):23533-43. doi: 10.1074/jbc.M111.247833. Epub 2011 May 10.
2
Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties.工程化生物合成具有改变的脱氧己糖部分的吉尔沃卡林类似物。
Appl Environ Microbiol. 2011 Jan;77(2):435-41. doi: 10.1128/AEM.01774-10. Epub 2010 Nov 12.
3
Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity.阐明吉尔菌素生物合成的最早步骤:GilP 和 GilQ 在起始单元特异性中的作用。
Org Biomol Chem. 2010 Sep 7;8(17):3851-6. doi: 10.1039/c0ob00036a. Epub 2010 Jul 8.
4
Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic.酶促全合成雷博霉素,一种蒽环类抗生素。
Org Lett. 2010 Jun 18;12(12):2814-7. doi: 10.1021/ol1009009.
5
Characterization of JadH as an FAD- and NAD(P)H-dependent bifunctional hydroxylase/dehydrase in jadomycin biosynthesis.JadH作为制霉素生物合成中一种依赖FAD和NAD(P)H的双功能羟化酶/脱水酶的特性分析。
Chembiochem. 2010 May 17;11(8):1055-60. doi: 10.1002/cbic.201000178.
6
Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters.裂霉素和金霉素生物合成基因簇的克隆与特性分析。
Chembiochem. 2010 Mar 1;11(4):523-32. doi: 10.1002/cbic.200900673.
7
GilR, an unusual lactone-forming enzyme involved in gilvocarcin biosynthesis.GilR,一种参与吉尔vocarcin生物合成的不寻常的内酯形成酶。
Chembiochem. 2009 May 25;10(8):1305-8. doi: 10.1002/cbic.200900130.
8
Plasticity in gilvocarcin-type C-glycoside pathways: discovery and antitumoral evaluation of polycarcin V from Streptomyces polyformus.吉尔vocarcin型C-糖苷途径的可塑性:来自多形链霉菌的聚癌菌素V的发现与抗肿瘤评估。
Org Biomol Chem. 2008 Oct 7;6(19):3601-5. doi: 10.1039/b808633h. Epub 2008 Jul 21.
9
Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity.吉尔vocarcin生物合成基因簇的酮还原酶gilU基因失活产生了具有部分改善生物活性的新类似物。
Chembiochem. 2009 Jan 26;10(2):278-86. doi: 10.1002/cbic.200800348.
10
Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027.在烯二炔类抗肿瘤抗生素C-1027生物合成过程中,SgcC3催化的(S)-β-酪氨酰-S-载体蛋白的区域特异性氯化反应
J Am Chem Soc. 2007 Oct 17;129(41):12432-8. doi: 10.1021/ja072311g. Epub 2007 Sep 22.

Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis.

作者信息

Pahari Pallab, Kharel Madan K, Shepherd Micah D, van Lanen Steven G, Rohr Jürgen

机构信息

Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536-0596, USA.

出版信息

Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1216-20. doi: 10.1002/anie.201105882. Epub 2011 Dec 23.

DOI:10.1002/anie.201105882
PMID:22223167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3343456/
Abstract
摘要