North East and North Central London Health Protection Unit, London, UK.
Influenza Other Respir Viruses. 2012 May;6(3):e35-41. doi: 10.1111/j.1750-2659.2011.00327.x. Epub 2012 Jan 11.
During the early containment phase in England from April to June 2009, the national strategy for H1N1 pandemic influenza involved case investigation and treatment, and tracing and prophylaxis of contacts.
To describe the relationship between early transmission of H1N1 pandemic influenza in London and age and socio-economic status.
Epidemiological data on cases of pandemic flu in London reported to the London Flu Response Centre were analysed to determine patterns of transmission.
There were 3487 reported cases (2202 confirmed, 1272 presumed and 14 probable) from 20 April to 28 June 2009, during the 'containment' period. The highest report rate of 206 per 100 000 (95% CI 195-218) was seen in primary school-age children (5-11 years) followed by 129 (95% CI 119-139) in secondary school-age children (12-18 years). Reports of cases were initially concentrated in affluent areas but overall showed a clear trend with deprivation and risk ratio of 2·32 (95% CI 1·94-2·78) between the most deprived and the least deprived.
Early transmissions were highest amongst school-aged children but linked with socio-economic deprivation across all age groups.
2009 年 4 月至 6 月，在英国的早期遏制阶段，针对 H1N1 大流行性流感的国家战略涉及病例调查和治疗、接触者追踪和预防。
描述 2009 年伦敦 H1N1 大流行性流感早期传播与年龄和社会经济地位之间的关系。
对向伦敦流感应对中心报告的大流行性流感病例的流行病学数据进行分析，以确定传播模式。
2009 年 4 月 20 日至 6 月 28 日“遏制”期间，报告了 3487 例病例（2202 例确诊，1272 例疑似，14 例可能）。小学年龄段（5-11 岁）的报告率最高，为每 10 万人 206 例（95%CI 195-218），其次是中学年龄段（12-18 岁）的 129 例（95%CI 119-139）。病例报告最初集中在富裕地区，但总体上呈明显的贫困趋势，最贫困地区与最不贫困地区的比值为 2.32（95%CI 1.94-2.78）。
大流行性流感早期传播率在学龄儿童中最高，但与所有年龄组的社会经济贫困有关。
