Indiana University School of Medicine, Indianapolis, IN, USA.
Ann Emerg Med. 2012 Jul;60(1):100-2. doi: 10.1016/j.annemergmed.2011.11.033. Epub 2012 Jan 10.
Serotonin syndrome is associated with use of certain street drugs, including methamphetamine, cocaine, and ecstasy. We describe a case of a woman who developed clinical findings consistent with serotonin syndrome after insufflation of 3,4-methylenedioxypyrovalerone (MDPV), a synthetic amphetamine. MDPV belongs to a group of substances called phenylethylamines, which are β-ketone analogs of other drugs of abuse, such as amphetamines and 3,4-methylenedioxymethamphetamine. She also received fentanyl initially during her hospitalization, which has also been associated with serotonin syndrome. In addition to benzodiazepines and supportive care, she was treated with cyproheptadine for 8 days, with slow resolution of her symptoms.
血清素综合征与某些街头毒品的使用有关，包括冰毒、可卡因和摇头丸。我们描述了一例女性患者，在吸入 3,4-亚甲二氧基吡咯戊酮（MDPV）后出现符合血清素综合征的临床发现，MDPV 属于一类称为苯乙胺的物质，是其他滥用药物（如安非他命和 3,4-亚甲二氧基甲基苯丙胺）的β-酮类似物。她在住院期间最初还接受了芬太尼治疗，芬太尼也与血清素综合征有关。除了苯二氮䓬类药物和支持性护理外，她还接受了赛庚啶治疗 8 天，症状缓慢缓解。
