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过去 12 个月有饮酒和非医疗用镇静剂使用史的人群的动机和同时使用镇静剂-酒精情况。

Motives and simultaneous sedative-alcohol use among past 12-month alcohol and nonmedical sedative users.

机构信息

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63108, USA.

出版信息

Am J Drug Alcohol Abuse. 2012 Jul;38(4):359-64. doi: 10.3109/00952990.2011.643987. Epub 2012 Jan 13.

Abstract

BACKGROUND

Simultaneous sedative-alcohol use (SSAU) is a matter of public health concern. It is important to address the various motives individuals may have for involvement in SSAU.

OBJECTIVE

To explore the motives associated with SSAU.

METHODS

Data were collected as part of the ongoing Prescription Drug Misuse, Abuse, and Dependence study in St. Louis. For this analysis, the sample included 173 participants who reported nonmedical sedative use for more than 5 days, and use of alcohol, in the past 12 months. SSAU was defined as past 12-month use of sedatives and alcohol together/at the same time.

RESULTS

Past 12-month SSAU was reported by 61% of the sample. Multivariate logistic regression indicated that for every increment of one motive, participants were significantly more likely to report SSAU (adjusted odds ratio (aOR): 1.30; 95% confidence interval (CI): 1.12-1.52). Furthermore, reporting sedative use "to get high, to change mood, to relieve stress, to party, and 'just because' " was independently associated with the past 12-month SSAU. Past 12-month SSAU was also found to be significantly associated with simultaneous use of sedatives and cannabis in the past 12 months.

CONCLUSION

A higher number of motives, as well as specific motives reported for sedative use, were found to be significantly associated with past 12-month SSAU.

SCIENTIFIC SIGNIFICANCE

Findings underscore the need for considering motives in tailoring preventive interventions for reducing SSAU. It may be equally important to direct efforts toward decreasing the number of motives, as well as addressing the specific motives reported for sedative use.

摘要

背景

同时使用镇静剂和酒精(SSAU)是一个公共卫生关注的问题。了解个人参与 SSAU 的各种动机非常重要。

目的

探索与 SSAU 相关的动机。

方法

数据是作为圣路易斯正在进行的处方药物滥用、滥用和依赖研究的一部分收集的。在这项分析中,样本包括 173 名报告过去 12 个月内非医疗镇静剂使用超过 5 天且使用过酒精的参与者。SSAU 被定义为过去 12 个月内同时使用镇静剂和酒精。

结果

样本中有 61%报告了过去 12 个月的 SSAU。多变量逻辑回归表明,对于每个动机的增量,参与者报告 SSAU 的可能性显著更高(调整后的优势比(aOR):1.30;95%置信区间(CI):1.12-1.52)。此外,报告镇静剂使用“为了获得快感、改变情绪、缓解压力、聚会和‘只是因为’”与过去 12 个月的 SSAU 独立相关。过去 12 个月的 SSAU 也与过去 12 个月同时使用镇静剂和大麻显著相关。

结论

更多的动机,以及报告的特定镇静剂使用动机,与过去 12 个月的 SSAU 显著相关。

科学意义

研究结果强调了在制定预防干预措施以减少 SSAU 时需要考虑动机。减少动机的数量以及解决报告的特定镇静剂使用动机可能同样重要。

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