Biological Psychiatry Division, Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria.
Curr Opin Psychiatry. 2012 Mar;25(2):71-5. doi: 10.1097/YCO.0b013e3283503624.
Social cognitive impairments are considered to be core features of schizophrenia and have been hypothesized to play a mediator role between basic neurocognition and patients' outcomes. In this context, theory of mind (ToM) abilities are of special relevance, and deficits in this area may represent trait markers of schizophrenia.
In this review, studies published since September 2010 have been summarized with a particular focus on the relationships between ToM and psychopathology, neurocognition, and psychosocial outcomes in patients with schizophrenia, as well as on ToM abilities in high-risk individuals. In addition, recent neuroimaging data as well as treatment interventions have been described.
The reviewed literature strengthens the hypothesis that ToM deficits have the potential to be valid markers for schizophrenia.
社会认知障碍被认为是精神分裂症的核心特征，据推测在基本神经认知和患者预后之间起中介作用。在这种情况下，心理理论（ToM）能力尤为重要，而该领域的缺陷可能代表精神分裂症的特征标志物。
在本次综述中，总结了自 2010 年 9 月以来发表的研究，特别关注精神分裂症患者的 ToM 与精神病理学、神经认知和心理社会预后之间的关系，以及高风险个体的 ToM 能力。此外，还描述了最近的神经影像学数据和治疗干预措施。
综述文献支持了这样一种假设，即 ToM 缺陷有可能成为精神分裂症的有效标志物。
