School of Biosciences and Biotechnologies, University of Camerino, Via Gentile III da Varano, IT-62032, Camerino.
Chem Biodivers. 2012 Jan;9(1):12-24. doi: 10.1002/cbdv.201100249.
The aim of this study was to verify the effectiveness of Achillea ligustica essential oils against several oral microorganisms in comparison with a commercial essential oil-containing mouthrinse (Listerine(®)) and clove oil (containing 89% eugenol). The inhibition efficacy of A. ligustica essential oils alone and in combination with Listerine(®) was evaluated by the micro-dilution method. The most susceptible microorganisms were Bacillus cereus, Streptococcus pyogenes, and Candida albicans. The efficacy was similar to that of the clove oil. The antiseptic mouthwash Listerine(®) did not exert a strong inhibition on microbial strains tested, whereas its effectiveness increased significantly when essential oil was added. The study provides additional evidence for the in vitro inhibitory activity of A. ligustica essential oils on several pathogens, suggesting their usefulness in mouthrinse formulations as an adjunct to mechanical oral hygiene regimens. Essential oil-containing mouthrinses can be beneficial, safe components of daily oral health routines, representing an efficient and without side effect alternative to prevent and control oral infections.
本研究旨在验证蓍草精油对几种口腔微生物的有效性，并将其与一种市售含精油漱口水（李施德林（®））和丁香油（含 89%丁香酚）进行比较。采用微量稀释法评估蓍草精油单独使用和与李施德林（®）联合使用的抑制效果。最易受影响的微生物是蜡状芽孢杆菌、化脓性链球菌和白色念珠菌。其效果与丁香油相似。抗菌漱口水李施德林（®）对所测试的微生物菌株没有很强的抑制作用，而当加入精油时，其效果显著增加。该研究为蓍草精油对几种病原体的体外抑制活性提供了额外的证据，表明其在漱口水配方中作为机械口腔卫生方案的辅助手段具有一定的用途。含精油的漱口水可以成为日常口腔健康护理方案中有益且安全的组成部分，是预防和控制口腔感染的一种高效且无副作用的替代方案。
