Londong W, Angerer M, Bosch R, Koelzow H
Department of Gastroenterology, Chirurgische Klinik Innenstadt, University of Munich, FRG.
Dig Dis. 1990;8 Suppl 1:46-53. doi: 10.1159/000171279.
In these prospective studies the influence of two different intragastric positions of electrodes and of four different compositions of standardized meals on 24-hour ambulatory pH recording were compared intraindividually in healthy male subjects. Simultaneous pH monitoring in 12 subjects demonstrated a more pronounced postprandial pH elevation in the fundus body compared to the antral area. The intraindividual comparison of an identical diet given on two different days to 10 subjects revealed nearly identical pH profiles. Variations of carbohydrate, protein and fat content of isocaloric meals given in a randomized order did not significantly alter 24-hour intragastric pH profiles. It is concluded from these data that positioning of the pH electrode in the fundus body area is superior to an antral position. 24-hour ambulatory intragastric pH monitoring in man is well reproducible. A strict standardization of the composition of meals is mandatory only for scientific investigations.
在这些前瞻性研究中，对健康男性受试者进行了个体内比较，观察了电极在胃内的两种不同位置以及四种不同标准化餐食组成对24小时动态pH记录的影响。对12名受试者的同步pH监测显示，与胃窦区域相比，胃底体部餐后pH升高更为明显。在两天内给10名受试者提供相同饮食并进行个体内比较，结果显示pH曲线几乎相同。以随机顺序提供等热量餐食中碳水化合物、蛋白质和脂肪含量的变化，并未显著改变24小时胃内pH曲线。从这些数据得出结论，pH电极置于胃底体部区域优于胃窦位置。人体24小时动态胃内pH监测具有良好的可重复性。只有在科学研究中才必须严格标准化餐食组成。
