荧光素眼底血管造影的自动几何配准

Automatic geometrical registration of fluorescein retinal angiograms.

作者信息

Jagoe R, Blauth C I, Smith P L, Arnold J V, Taylor K, Wootton R

机构信息

Department of Medical Physics, Royal Postgraduate Medical School, Hammersmith Hospital, London, England.

出版信息

Comput Biomed Res. 1990 Oct;23(5):403-9. doi: 10.1016/0010-4809(90)90030-g.

DOI:10.1016/0010-4809(90)90030-g

PMID:2225786

Abstract

Changes in retinal microvascular perfusion revealed by fluorescein angiography have been reported in patients undergoing coronary artery surgery. Quantification of these changes is important and current techniques depend on careful visual inspection of the angiograms by humans. Computer image processing methods can be used to identify and highlight differences, but geometrical registration of the images is a prerequisite to the comparisons. Automatic methods for locating and matching reference points have therefore been developed. In combination with an iterative process which used least-squares error to calculate the transformation coefficients, subsets of reference points were selected and used to register successfully 20 image pairs.

摘要

据报道，接受冠状动脉手术的患者经荧光血管造影显示视网膜微血管灌注发生了变化。对这些变化进行量化很重要，而目前的技术依赖于人工对血管造影进行仔细的目视检查。计算机图像处理方法可用于识别和突出差异，但图像的几何配准是进行比较的前提条件。因此，已开发出用于定位和匹配参考点的自动方法。结合使用最小二乘误差来计算变换系数的迭代过程，选择了参考点子集，并成功地对20对图像进行了配准。