Neurological Unit, University of Erlangen-Nuremberg at Erlangen, Neurologische Universitätsklinik, Schwabachanlage 6, 91054 Erlangen, Germany.
J Neurol. 2012 Aug;259(8):1655-61. doi: 10.1007/s00415-011-6394-1. Epub 2012 Jan 19.
Repetition is frequently impaired in aphasia, most strikingly in conduction aphasia. The still not fully answered question is whether this relates to a linguistic deficit or to a general impairment of working memory extending to other modalities as well. To contribute to this problem, we assessed 49 aphasic and 50 non-aphasic stroke patients using an aphasia test plus three memory tests in forward and backward fashion, taxing verbal, numerical, spatial, and facial retention. The results show that in aphasics there is a memory gradient declining gradually from verbal to nonverbal content reflecting aphasia severity and that aphasics generally perform worse than non-aphasics, even if they present with similar cerebral lesions.
失语症患者经常表现出重复能力受损,在传导性失语症中最为明显。目前仍未完全解答的问题是,这种情况是与语言缺陷有关,还是与工作记忆的普遍损伤有关,这种损伤还会延伸到其他感觉模式。为了解决这个问题,我们使用失语症测试和三种向前和向后的记忆测试评估了 49 名失语症和 50 名非失语症中风患者,测试内容包括语言、数字、空间和面部记忆保留。结果表明,在失语症患者中,存在一个从语言内容逐渐下降到非语言内容的记忆梯度,反映了失语症的严重程度,而且即使患者的大脑损伤相似,失语症患者的表现也普遍比非失语症患者差。