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估算加拿大的不孕不育患病率。

Estimating the prevalence of infertility in Canada.

机构信息

Health Analysis Division, Statistics Canada, Ottawa, Canada K1A 0T6.

出版信息

Hum Reprod. 2012 Mar;27(3):738-46. doi: 10.1093/humrep/der465. Epub 2012 Jan 17.

DOI:10.1093/humrep/der465
PMID:22258658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3279129/
Abstract

BACKGROUND

Over the past 10 years, there has been a significant increase in the use of assisted reproductive technologies in Canada, however, little is known about the overall prevalence of infertility in the population. The purpose of the present study was to estimate the prevalence of current infertility in Canada according to three definitions of the risk of conception.

METHODS

Data from the infertility component of the 2009-2010 Canadian Community Health Survey were analyzed for married and common-law couples with a female partner aged 18-44. The three definitions of the risk of conception were derived sequentially starting with birth control use in the previous 12 months, adding reported sexual intercourse in the previous 12 months, then pregnancy intent. Prevalence and odds ratios of current infertility were estimated by selected characteristics.

RESULTS

Estimates of the prevalence of current infertility ranged from 11.5% (95% CI 10.2, 12.9) to 15.7% (95% CI 14.2, 17.4). Each estimate represented an increase in current infertility prevalence in Canada when compared with previous national estimates. Couples with lower parity (0 or 1 child) had significantly higher odds of experiencing current infertility when the female partner was aged 35-44 years versus 18-34 years. Lower odds of experiencing current infertility were observed for multiparous couples regardless of age group of the female partner, when compared with nulliparous couples.

CONCLUSIONS

The present study suggests that the prevalence of current infertility has increased since the last time it was measured in Canada, and is associated with the age of the female partner and parity.

摘要

背景

在过去的 10 年中,加拿大辅助生殖技术的使用显著增加,然而,人们对人群中整体不孕不育的流行率知之甚少。本研究的目的是根据受孕风险的三种定义,估计加拿大目前不孕不育的流行率。

方法

对 2009-2010 年加拿大社区健康调查中不孕不育部分的已婚和同居伴侣(女性伴侣年龄在 18-44 岁)的数据进行了分析。受孕风险的三种定义是依次从过去 12 个月中使用避孕药具开始,然后加入过去 12 个月中报告的性行为,再加上怀孕意图。通过选择的特征来估计当前不孕不育的流行率和优势比。

结果

当前不孕不育的流行率估计值在 11.5%(95%CI 10.2,12.9)到 15.7%(95%CI 14.2,17.4)之间。与之前的全国估计值相比,每个估计值都代表加拿大当前不孕不育流行率的增加。当女性伴侣年龄在 35-44 岁时,与 18-34 岁相比,生育力较低(0 或 1 个孩子)的夫妇经历当前不孕不育的几率明显更高。与未生育的夫妇相比,无论女性伴侣的年龄组如何,多产的夫妇经历当前不孕不育的几率都较低。

结论

本研究表明,自上次在加拿大测量以来,当前不孕不育的流行率有所增加,且与女性伴侣的年龄和生育次数有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/3279129/00f2ad256a02/der46502.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/3279129/00040481de81/der46501.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/3279129/00f2ad256a02/der46502.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/3279129/00040481de81/der46501.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/3279129/00f2ad256a02/der46502.jpg

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3
Assisted reproductive technologies (ART) in Canada: 2007 results from the Canadian ART Register.加拿大的辅助生殖技术(ART):2007 年加拿大 ART 登记处的结果。
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4
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Biol Reprod. 2025 Jun 15;112(6):1134-1147. doi: 10.1093/biolre/ioaf062.
5
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