Department of Civil and Environmental Engineering, Faculty of Engineering, Mahidol University, Phutthamonthon, Nakorn Pathom, Thailand.
J Hazard Mater. 2012 Feb 29;205-206:139-43. doi: 10.1016/j.jhazmat.2011.12.050. Epub 2012 Jan 9.
This research aimed to monitor the amounts of PFOS and PFOA in food packaging and study the migration of PFOS and PFOA from food packaging, using a saliva simulant and pressurized liquid extraction (PLE) technique. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was employed to determine residues of PFOS and PFOA by using a gradient reversed-phase method with ammonium acetate/acetonitrile buffer. A good linearity was established for PFOS and PFOA in a range of 0.05-10 μgL(-1), with R2 ≥ 0.9998. Of the samples extracted by methanol, the highest concentration of PFOS was found in fast-food container samples, at a level of 92.48 ng dm(-2). For PFOA, the highest concentration in samples extracted by methanol was found in ice cream cup samples, at a level of 16.91 ng dm(-2). The amounts of PFOS and PFOA that migrated from food packaging samples through contact with saliva simulant were 4.80 and 4.55 ng dm(-2), respectively. Saliva simulant could leach PFOS and PFOA from the group of the thickest paper samples (≤1 dm2 g(-1)) at levels of 7.01 and 6.41 ng dm(-2), respectively, indicating that paper with greater thickness and less area might release larger quantities of coated/added PFOS or PFOA.
本研究旨在监测食品包装中全氟辛烷磺酸（PFOS）和全氟辛酸（PFOA）的含量，并使用唾液模拟物和加压液体萃取（PLE）技术研究 PFOS 和 PFOA 从食品包装中的迁移情况。采用梯度反相法，以乙酸铵/乙腈缓冲液为流动相，用液相色谱-串联质谱法（LC-MS/MS）测定 PFOS 和 PFOA 的残留量。PFOS 和 PFOA 在 0.05-10 μgL(-1) 范围内呈良好线性关系，R2≥0.9998。从甲醇提取的样品中，快餐容器样品中 PFOS 的浓度最高，为 92.48 ng dm(-2)。对于 PFOA，甲醇提取的样品中浓度最高的是冰淇淋杯样品，为 16.91 ng dm(-2)。通过与唾液模拟物接触，从食品包装样品中迁移出的 PFOS 和 PFOA 分别为 4.80 和 4.55 ng dm(-2)。唾液模拟物可以从最厚的纸样品（≤1 dm2 g(-1)）中浸出 PFOS 和 PFOA，浓度分别为 7.01 和 6.41 ng dm(-2)，这表明厚度较大、面积较小的纸张可能会释放出更多的涂覆/添加 PFOS 或 PFOA。
