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用于增强肿瘤成像的新型量子点

Novel Quantum Dots for Enhanced Tumor Imaging.

作者信息

Nair Ashwin, Shen Jinhui, Thevenot Paul, Cai Tong, Hu Zhibing, Tang Liping

机构信息

Department of Bioengineering, University of Texas at Arlington.

出版信息

Proc IEEE Conf Nanotechnol. 2008 Aug 18;8:650-653. doi: 10.1109/NANO.2008.197.

DOI:10.1109/NANO.2008.197
PMID:22267976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3261784/
Abstract

So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.

摘要

为了开发一种有效的肿瘤成像工具，我们将量子点（QD）嵌入水凝胶纳米颗粒中。已经在体外和小鼠肿瘤模型中研究了它们在癌细胞中的摄取情况。与单独的量子点相比，嵌入纳米颗粒中的量子点在肿瘤组织中显示出更高的摄取率。这种新型共轭物可以作为一种良好的成像工具，并且还具有作为药物载体的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/680c69da6060/nihms339294f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/82539454b1b9/nihms339294f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/a1610868b0cc/nihms339294f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/16ea191acc97/nihms339294f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/935f66c0de72/nihms339294f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/43838fd839a2/nihms339294f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/680c69da6060/nihms339294f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/82539454b1b9/nihms339294f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/a1610868b0cc/nihms339294f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/16ea191acc97/nihms339294f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/935f66c0de72/nihms339294f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/43838fd839a2/nihms339294f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360a/3261784/680c69da6060/nihms339294f6.jpg

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本文引用的文献

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