University of Montpellier 3, Laboratory Epsylon, Montpellier, France.
Qual Life Res. 2013 Feb;22(1):119-22. doi: 10.1007/s11136-012-0113-y. Epub 2012 Jan 25.
The purpose of this study was to evaluate the reliability and validity of the Caregivers Quality of Life Cancer index scale (CQoLC) in a sample of spouses of French cancer patients.
The CQoLC, the Medical Outcomes Study Short Form 12 (MOS SF-12) and the State-Trait Anxiety Inventory (STAI) were administered to 300 spouses aged 21-85 years. Clinical data such as severity of cancer, medical treatment and duration of illness were obtained from a review of medical records.
An exploratory factor analysis yielded a 23-item measure with one factor explaining 38.76% of the variance: labeled impairment of quality of life. The correlations between this factor and MOS SF-12 were negative for the physical component (ρ = -0.351, p < 0.001) and positive for the mental component (ρ = 0.184, p < 0.005). One-way ANOVA with STAI scores indicated good discriminant validity (F[2, 237] = 4.80, p < 0.01, η(2) = 0.04). Participants with low anxiety had a better quality of life than those with moderate and high anxiety.
The findings indicate that the CQoLC has sufficient validity and reliability to assess the impairment of quality of life in spouses of French cancer patients.
本研究旨在评估配偶癌症患者生活质量指数量表（CQoLC）在法国癌症患者配偶样本中的信度和效度。
对 300 名年龄在 21-85 岁的配偶进行了 CQoLC、医疗结局研究短式 12 项量表（MOS SF-12）和状态-特质焦虑量表（STAI）的评估。临床数据如癌症严重程度、医疗治疗和疾病持续时间均来自病历回顾。
探索性因子分析得出了一个包含 23 个项目的测量工具，其中一个因子解释了 38.76%的方差：生活质量受损。该因子与 MOS SF-12 的相关性在生理成分上呈负相关（ρ=-0.351，p<0.001），在心理成分上呈正相关（ρ=0.184，p<0.005）。基于 STAI 评分的单因素方差分析表明具有良好的区分效度（F[2, 237]=4.80，p<0.01，η²=0.04）。焦虑程度低的参与者生活质量优于焦虑程度中、高的参与者。
研究结果表明，CQoLC 具有足够的信度和效度，可用于评估法国癌症患者配偶的生活质量受损情况。
