Dipartimento Farmaco Chimico Tecnologico, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy.
J Nat Prod. 2012 Feb 24;75(2):225-9. doi: 10.1021/np2009219. Epub 2012 Jan 25.
Bioactivity-guided fractionation of a dichloromethane extract of the leaves of Myrtus communis led to the isolation of phloroglucinol derivatives. The structures of the new myrtucommulones J, K, and L (1-3) and the previously known myrtucommulone A (4) were elucidated on the basis of extensive 1D and 2D NMR experiments as well as high-resolutionmass spectrometry. Myrtucommulone J was obtained as a tautomeric pair (1/1a). The compounds were tested in vitro for their cytotoxic and antibacterial activities.
生物活性导向分离桃金娘科植物叶片的二氯甲烷提取物得到了苯丙素衍生物。新的桃金娘烯酮 J、K 和 L（1-3）以及先前已知的桃金娘烯酮 A（4）的结构是基于广泛的 1D 和 2D NMR 实验以及高分辨率质谱确定的。桃金娘烯酮 J 是作为互变异构体对（1/1a）获得的。对这些化合物进行了体外细胞毒性和抗菌活性测试。
