In Vitro Antibacterial Activity of L. and L. Leaves against and .

MATERIALS AND METHODS

Clinical strains of and and two reference strains of were tested. The antibacterial activity of each studied plant extract was evaluated using agar diffusion and broth microdilution assays.

RESULTS

Both aqueous and methanolic extracts of exhibited high antibacterial activity against periodontal pathogens as compared to extracts. At concentrations of 2.5-0.32 mg/disc, inhibition zones of the methanolic extract of ranged from 19.66 ± 0.57 to 12.33 ± 0.57 mm. The methanolic extract of showed at concentrations of 5-0.63 mg/disc inhibition zones ranging from 15.66 ± 0.57 to 12 ± 0.00 mm. Its aqueous extract at concentration of 0.63 mg/disc showed no antimicrobial activity against the clinical and reference strain of . This study showed that methanolic and aqueous extracts of and have in vitro an antibacterial activity against periodontal pathogens. They could be use as ingredients of an oral antimicrobial agent for prevention or treatment of periodontal diseases. Further research on isolating the compounds from these plant extracts and their toxicity effect could be conducted.