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紧张症与酒精戒断:一种复杂且被低估的综合征。

Catatonia and alcohol withdrawal: a complex and underestimated syndrome.

机构信息

Univ Lille Nord de France, France.

出版信息

Alcohol Alcohol. 2012 May-Jun;47(3):288-90. doi: 10.1093/alcalc/agr170. Epub 2012 Jan 25.

Abstract

AIMS

Catatonia is a neuropsychiatric syndrome characterized by alterations in motor behavior, vigilance, thought and mood. Catatonia syndrome occurs in many neuropsychiatric and medical conditions, but it is very rarely mentioned as occurring during alcohol withdrawal. We think that this co-occurrence could be underestimated in clinics because alcohol withdrawal symptoms may distract from its identification.

METHODS

We report the case of a patient presenting with catatonia during the benzodiazepine reduction period of alcohol detoxification.

RESULTS

A 65-year-old woman presented with a 15-year history of alcohol dependence and developed catatonic episodes several times during alcohol withdrawal treatment. Misdiagnosis delayed specific treatment. Symptoms of episodes dramatically improved 48 h after treatment with diazepam and revealed an anxiety disorder.

CONCLUSION

This report confirms that catatonia is a non-specific response to psychological, physical and psychosocial stress factors. Recent alcohol withdrawal may sensitize the patient to benzodiazepine withdrawal catatonia, and this phenomenon is probably underestimated. Catatonia Rating Scales can be useful when diagnosis is complicated as in alcohol and benzodiazepine withdrawal. In that situation, misdiagnosis is common and may delay specific treatment.

摘要

目的

紧张症是一种以运动行为、警觉性、思维和情绪改变为特征的神经精神综合征。紧张症综合征发生在许多神经精神和医学状况中,但在酒精戒断期间很少被提及。我们认为,这种同时发生的情况在临床上可能被低估了,因为酒精戒断症状可能会分散对其识别的注意力。

方法

我们报告了一例在苯二氮䓬类药物减少酒精解毒期间出现紧张症的患者。

结果

一名 65 岁女性有 15 年的酒精依赖史,在酒精戒断治疗期间多次出现紧张症发作。误诊导致特定治疗延迟。在接受地西泮治疗 48 小时后,发作症状明显改善,并出现焦虑障碍。

结论

本报告证实紧张症是对心理、身体和心理社会应激因素的非特异性反应。近期酒精戒断可能使患者对苯二氮䓬类药物戒断性紧张症敏感,这种现象可能被低估了。在诊断复杂的情况下,如酒精和苯二氮䓬类药物戒断时,紧张症评定量表可能很有用。在这种情况下,误诊很常见,可能会延迟特定的治疗。

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