以色列 Kinneret 湖铜绿微囊藻水华材料的代谢物。
Metabolites of Microcystis aeruginosa bloom material from Lake Kinneret, Israel.
机构信息
Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel-Aviv University, Ramat Aviv, Tel-Aviv 69978, Israel.
出版信息
J Nat Prod. 2012 Feb 24;75(2):209-19. doi: 10.1021/np200909x. Epub 2012 Jan 26.
Six new metabolites, micropeptin KT1042, microguanidine KT636, aeruginosins KT608A, KT608B, and KT650, and pseudoaeruginosin KT554, were isolated along with the known micropeptins SF909 and HM978, cyanopeptolin S, anabaenopeptin F, and the two isomers of planktocyclin-S-oxide from a bloom material collected from Lake Kinneret, Israel, in March 2005. The structure elucidation and biological activity of the six new natural products isolated from this bloom material and the related aeruginosin GH553 are described.
从 2005 年 3 月以色列 Kinneret 湖的水华材料中分离到六种新的代谢产物，包括 micropeptin KT1042、microguanidine KT636、aeruginosins KT608A、KT608B 和 KT650 以及 pseudoaeruginosin KT554，以及已知的 micropeptins SF909 和 HM978、cyanopeptolin S、anabaenopeptin F 和 planktocyclin-S-oxide 的两种异构体。本文描述了从该水华材料中分离到的六种新天然产物的结构阐明和生物活性，以及相关的 aeruginosin GH553。
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