Pantel M, Guntinas-Lichius O
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Friedrich-Schiller-Universität, Lessingstr. 2, 07740, Jena, Deutschland.
HNO. 2012 Jan;60(1):32-40. doi: 10.1007/s00106-011-2423-8.
Laryngeal cancer is one of the most frequent types of head and neck cancer. The incidence is decreasing for men but still increasing for women. The incidence in Germany is about 5-7/100,000 persons/year for men and 0.6-0.8/100,000 persons/year for women. Due to the increased life expectancy, the average age of patients diagnosed with laryngeal cancer is increasing. Nevertheless, adequately prepared older patients treated by standard protocols can have the same survival and complication rates as younger patients. Tobacco and alcohol are still the primary risk factors responsible for disease in at least 80% of the patients. Despite the many new diagnostic tools, still more than half of the patients are diagnosed at an advanced tumor stage. Survival rates have not improved significantly in the last 10 years in Germany, and the average 5-year overall survival rate is about 60%. However, a decrease in the survival rate, as observed in the USA, cannot be confirmed for Germany.
喉癌是头颈部最常见的癌症类型之一。男性发病率呈下降趋势，但女性发病率仍在上升。德国男性发病率约为每年5-7/10万人，女性为每年0.6-0.8/10万人。由于预期寿命延长，被诊断为喉癌的患者平均年龄在增加。然而，采用标准方案进行充分准备的老年患者与年轻患者的生存率和并发症发生率相同。烟草和酒精仍然是至少80%患者患病的主要危险因素。尽管有许多新的诊断工具，但仍有超过一半的患者在肿瘤晚期才被诊断出来。在德国，过去10年生存率没有显著提高，5年总生存率平均约为60%。然而，在美国观察到的生存率下降情况在德国并未得到证实。
