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垂直骨增量后下颌骨中短种植体与长种植体的比较:一项随机对照试验加载8年后的结果

Short implants versus longer implants in vertically augmented posterior mandibles: result at 8 years after loading from a randomised controlled trial.

作者信息

Felice Pietro, Barausse Carlo, Pistilli Roberto, Ippolito Daniela Rita, Esposito Marco

出版信息

Eur J Oral Implantol. 2018;11(4):385-395.

Abstract

PURPOSE

To evaluate whether 6.6-mm long implants could be a suitable alternative to longer implants placed in vertically augmented atrophic posterior mandibles.

MATERIALS AND METHODS

Sixty partially edentulous patients having 7 to 8 mm of residual crestal height and at least 5.5-mm thickness measured on computed tomography scans above the mandibular canal were randomly allocated according to a parallel-group design either to receive one to three submerged 6.6-mm long implants or 9.6-mm or longer implants (30 patients per group) placed in vertically augmented bone. Bone was augmented with interpositional anorganic bovine bone blocks fixed with titanium plates and covered with resorbable barriers. Grafts were left to heal for 5 months before implant placement. Four months after implant placement, provisional acrylic prostheses were delivered, replaced, after 4 months, by definitive metal-ceramic prostheses. Outcome measures were: prosthesis and implant failures, complications, and radiographic peri-implant marginal bone level changes. Patients were followed up to 8 years after loading.

RESULTS

Eight years after loading 12 patients dropped out, five from the short implant group and seven from the augmented group. The augmentation procedure failed in two patients and only 6.6-mm long implants could be inserted. There were no statistically significant differences for prosthesis and implant failures. Four prostheses failed in three patients of the short implant group versus three prostheses in three patients of the augmented group (Fisher exact test P = 1.000; difference in proportions = 0.01; 95% CI: -0.19 to 0.22). Five short implants failed in three patients versus three long implants in three patients (Fisher exact test P = 1.000; difference in proportions = 0.01; 95% CI: -0.19 to 0.22). There were statistically more complications in augmented patients (27 complications in 22 augmented patients versus 9 complications in 8 patients of the short implant group) (Fisher exact test P < 0.001; difference in proportions = 0.64; 95% CI: 0.38 to 0.79). Both groups gradually lost peri-implant bone in a statistically significant way. Eight years after loading, short implant group patients lost an average of 1.58 mm of peri-implant bone compared with 2.46 mm in the augmented group. Short implants experienced statistically significantly less bone loss (0.88 mm, 95% CI: 0.50 to 1.26 mm) than long implants.

CONCLUSIONS

When residual bone height over the mandibular canal is between 7 and 8 mm, 6.6-mm short implants are an interesting alternative to vertical augmentation in posterior atrophic mandibles since the treatment is faster, cheaper and associated with less morbidity.

摘要

目的

评估6.6毫米长的种植体是否可作为植入垂直骨增量后的萎缩性下颌后牙区较长种植体的合适替代方案。

材料与方法

60例部分牙列缺失患者,其剩余牙槽嵴高度为7至8毫米,在下颌管上方的计算机断层扫描测量至少有5.5毫米厚,根据平行组设计随机分配,分别接受1至3颗埋入式6.6毫米长的种植体或9.6毫米或更长的种植体(每组30例患者),种植体植入垂直骨增量后的骨内。使用钛板固定的无机牛骨块进行骨增量,并覆盖可吸收屏障。在植入种植体前,让植骨愈合5个月。种植体植入4个月后,交付临时丙烯酸修复体,4个月后更换为最终的金属陶瓷修复体。观察指标包括:修复体和种植体失败情况、并发症以及种植体周围边缘骨水平的影像学变化。患者在负重后随访8年。

结果

负重8年后,12例患者退出研究,短种植体组5例,骨增量组7例。2例患者的骨增量手术失败,仅能植入6.6毫米长的种植体。修复体和种植体失败情况无统计学显著差异。短种植体组3例患者的4个修复体失败,而骨增量组3例患者的3个修复体失败(Fisher精确检验P = 1.000;比例差异 = 0.01;95%可信区间:-0.19至0.22)。短种植体组3例患者的5个短种植体失败,而骨增量组3例患者的3个长种植体失败(Fisher精确检验P = 1.000;比例差异 = 0.01;95%可信区间:-0.19至0.22)。骨增量患者的并发症在统计学上更多(22例骨增量患者中有27例并发症,而短种植体组8例患者中有9例并发症)(Fisher精确检验P < 0.001;比例差异 = 0.64;95%可信区间:0.38至0.79)。两组种植体周围骨均以统计学显著方式逐渐丧失。负重8年后,短种植体组患者种植体周围骨平均丧失1.58毫米,而骨增量组为2.46毫米。短种植体的骨丧失在统计学上显著少于长种植体(0.88毫米,95%可信区间:0.50至1.26毫米)。

结论

当下颌管上方的剩余骨高度在7至8毫米之间时,6.6毫米的短种植体是后牙区萎缩性下颌骨垂直骨增量的一个有吸引力的替代方案,因为该治疗更快、更便宜且发病率更低。

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