南非海洋软体动物 Siphonaria oculus 的聚丙酸盐。

Polypropionates from the South African marine mollusk Siphonaria oculus.

机构信息

Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa.

出版信息

J Nat Prod. 2012 Mar 23;75(3):497-501. doi: 10.1021/np2009384. Epub 2012 Jan 27.

DOI:10.1021/np2009384

Abstract

Three new polypropionate metabolites, 6Z,8E-Δ(8)-siphonarienfuranone (1), 6E,8E-Δ(8)-siphonarienfuranone (2), and 6E,8E-3-hydroxy-4,6,8,10,12-pentamethylpentadeca-6,8-dien-5-one (3), and the known polypropionate siphonarienfuranone (4) were isolated from the intertidal South African marine mollusk Siphonaria oculus. Evidence is presented to suggest that 1, 2, and 4 may cyclize from an acylic precursor on chromatographic workup of the acetone extract of this mollusk.

摘要

从南非潮间带海洋软体动物 Siphonaria oculus 中分离得到三个新的聚丙酸盐代谢物：6Z,8E-Δ(8)-siphonarienfuranone (1)、6E,8E-Δ(8)-siphonarienfuranone (2)和 6E,8E-3-羟基-4,6,8,10,12-五甲基十五碳-6,8-二烯-5-酮 (3)，以及已知的聚丙酸盐 siphonarienfuranone (4)。有证据表明，在对这种软体动物的丙酮提取物进行色谱处理时，1、2 和 4 可能会从无环前体环化。