子宫内膜干细胞与生殖
Endometrial stem cells and reproduction.
作者信息
Morelli Sara S, Yi Pauline, Goldsmith Laura T
机构信息
Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA.
出版信息
Obstet Gynecol Int. 2012;2012:851367. doi: 10.1155/2012/851367. Epub 2012 Jan 12.
Abstract
Abnormal endometrial function remains a significant cause of implantation failure, recurrent pregnancy loss, and other pathologies responsible for female infertility. The development of novel therapies to treat infertility due to endometrial dysfunction requires an understanding of the latest advancements in endometrial cell biology, such as the role of endometrial stem cells. The remarkable regenerative capacity of the human endometrium is absolutely essential for successful reproduction and likely requires a population of stem cells in the endometrium. The purpose of this review is to provide an introduction to some of the newest concepts in endometrial stem cell biology.
摘要
子宫内膜功能异常仍然是着床失败、复发性流产以及导致女性不孕的其他病理状况的重要原因。开发治疗因子宫内膜功能障碍导致的不孕症的新疗法需要了解子宫内膜细胞生物学的最新进展，例如子宫内膜干细胞的作用。人类子宫内膜卓越的再生能力对于成功受孕绝对至关重要，而且子宫内膜可能需要一群干细胞。本综述的目的是介绍一些子宫内膜干细胞生物学的最新概念。
相似文献
1
Endometrial stem cells and reproduction.子宫内膜干细胞与生殖
Obstet Gynecol Int. 2012;2012:851367. doi: 10.1155/2012/851367. Epub 2012 Jan 12.
2
Implications of telomeres and telomerase in endometrial pathology.端粒和端粒酶在子宫内膜病理学中的意义。
Hum Reprod Update. 2017 Mar 1;23(2):166-187. doi: 10.1093/humupd/dmw044.
3
Regenerating endometrium from stem/progenitor cells: is it abnormal in endometriosis, Asherman's syndrome and infertility?从干细胞/祖细胞再生子宫内膜：在子宫内膜异位症、Asherman 综合征和不孕中是否异常？
Curr Opin Obstet Gynecol. 2013 Jun;25(3):193-200. doi: 10.1097/GCO.0b013e32836024e7.
4
Endometrial side population cells: potential adult stem/progenitor cells in endometrium.子宫内膜侧群细胞：子宫内膜中潜在的成体干/祖细胞
Biol Reprod. 2015 Oct;93(4):84. doi: 10.1095/biolreprod.115.131490. Epub 2015 Aug 26.
5
The role of mesenchymal-epithelial transition in endometrial function.间质-上皮转化在子宫内膜功能中的作用。
Hum Reprod Update. 2019 Jan 1;25(1):114-133. doi: 10.1093/humupd/dmy035.
6
Endometrial Stem Cell Markers: Current Concepts and Unresolved Questions.子宫内膜干细胞标志物：当前概念与未决问题。
Int J Mol Sci. 2018 Oct 19;19(10):3240. doi: 10.3390/ijms19103240.
7
The motile and invasive capacity of human endometrial stromal cells: implications for normal and impaired reproductive function.人类子宫内膜基质细胞的运动和侵袭能力：对正常和受损生殖功能的影响。
Hum Reprod Update. 2013 Sep-Oct;19(5):542-57. doi: 10.1093/humupd/dmt025. Epub 2013 Jul 4.
8
Endometrial stem/progenitor cells and proliferative disorders of the endometrium.子宫内膜干细胞/祖细胞与子宫内膜增殖性疾病
Minerva Ginecol. 2006 Dec;58(6):511-26.
9
Therapeutic strategies involving uterine stem cells in reproductive medicine.生殖医学中涉及子宫干细胞的治疗策略。
Curr Opin Obstet Gynecol. 2018 Jun;30(3):209-216. doi: 10.1097/GCO.0000000000000457.
10
Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy loss.进化正向基因组学揭示了复发性早期妊娠丢失中失调的基因和通路的新见解。
Hum Reprod. 2015 Mar;30(3):519-29. doi: 10.1093/humrep/deu355. Epub 2015 Jan 12.
引用本文的文献
1
Research progress of stem cell therapy for endometrial injury.子宫内膜损伤的干细胞治疗研究进展
Mater Today Bio. 2022 Aug 8;16:100389. doi: 10.1016/j.mtbio.2022.100389. eCollection 2022 Dec.
2
Effects of smoking on the tissue regeneration-associated functions of human endometrial stem cells via a novel target gene SERPINB2.通过新型靶基因 SERPINB2 研究吸烟对人子宫内膜干细胞组织再生相关功能的影响。
Stem Cell Res Ther. 2022 Aug 5;13(1):404. doi: 10.1186/s13287-022-03061-1.
3
Effect of MiR-100-5p on proliferation and apoptosis of goat endometrial stromal cell in vitro and embryo implantation in vivo.miR-100-5p 对山羊子宫内膜基质细胞体外增殖和凋亡及体内胚胎着床的影响。
J Cell Mol Med. 2022 May;26(9):2543-2556. doi: 10.1111/jcmm.17226. Epub 2022 Apr 12.
4
The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB2.细颗粒物 (PM) 通过其关键调节因子 SERPINB2 对人子宫内膜干细胞的各种有益功能的影响。
Exp Mol Med. 2021 Dec;53(12):1850-1865. doi: 10.1038/s12276-021-00713-9. Epub 2021 Dec 2.
5
Noncanonical functions of glucocorticoids: A novel role for glucocorticoids in performing multiple beneficial functions in endometrial stem cells.糖皮质激素的非经典功能：糖皮质激素在子宫内膜干细胞中发挥多种有益功能的新作用。
Cell Death Dis. 2021 Jun 12;12(6):612. doi: 10.1038/s41419-021-03893-4.
6
Preventive Effects of Intrauterine Injection of Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Media on Uterine Fibrosis Immediately after Endometrial Curettage in Rabbit.兔子宫内膜刮宫术后立即宫腔注射骨髓间充质基质细胞条件培养基对子宫纤维化的预防作用
Stem Cells Int. 2020 Nov 7;2020:8849537. doi: 10.1155/2020/8849537. eCollection 2020.
7
Regenerative Potential of Menstrual Blood-Derived Stem Cells and Platelet-Derived Growth Factor in Endometrial Injury.月经血来源干细胞和血小板衍生生长因子在内膜损伤中的再生潜能。
Med Sci Monit. 2020 Feb 29;26:e919251. doi: 10.12659/MSM.919251.
8
An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2.一种内源性抗衰老因子，Sonic Hedgehog，通过 SERPINB2 抑制子宫内膜干细胞衰老。
Mol Ther. 2019 Jul 3;27(7):1286-1298. doi: 10.1016/j.ymthe.2019.04.019. Epub 2019 Apr 27.
9
Double-edged sword of gonadotropin-releasing hormone (GnRH): A novel role of GnRH in the multiple beneficial functions of endometrial stem cells.促性腺激素释放激素（GnRH）的双刃剑：GnRH 在子宫内膜干细胞的多种有益功能中的新作用。
Cell Death Dis. 2018 Aug 1;9(8):828. doi: 10.1038/s41419-018-0892-3.
10
Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function.小鼠子宫中转化生长因子β受体1的组成性激活会损害子宫形态和功能。
Biol Reprod. 2015 Feb;92(2):34. doi: 10.1095/biolreprod.114.125146. Epub 2014 Dec 10.
本文引用的文献
1
Reconstruction of endometrium from human endometrial side population cell lines.从人子宫内膜侧群细胞系重建子宫内膜。
PLoS One. 2011;6(6):e21221. doi: 10.1371/journal.pone.0021221. Epub 2011 Jun 21.
2
Stem cells in human endometrium and endometrial carcinoma.人子宫内膜和子宫内膜癌中的干细胞。
Int J Gynecol Pathol. 2011 Jul;30(4):317-27. doi: 10.1097/PGP.0b013e3182102754.
3
CD34+ hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells.人子宫内膜中存在 CD34+造血前体细胞，与基质细胞相互作用后可分化为自然杀伤细胞。
Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2402-7. doi: 10.1073/pnas.1016257108. Epub 2011 Jan 19.
4
Adult stem cells in the endometrium.子宫内膜中的成人干细胞。
Mol Hum Reprod. 2010 Nov;16(11):818-34. doi: 10.1093/molehr/gaq061. Epub 2010 Jul 13.
5
Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells.人类子宫内膜侧群细胞表现出体干细胞的基因型、表型和功能特征。
PLoS One. 2010 Jun 24;5(6):e10964. doi: 10.1371/journal.pone.0010964.
6
Human uterine stem/progenitor cells: their possible role in uterine physiology and pathology.人子宫内膜干细胞/祖细胞：其在子宫生理学和病理学中的可能作用。
Reproduction. 2010 Jul;140(1):11-22. doi: 10.1530/REP-09-0438. Epub 2010 May 10.
7
Reepithelialization of the uterine surface arises from endometrial glands: evidence from a functional mouse model of breakdown and repair.子宫表面的再上皮化源于子宫内膜腺体：来自破坏和修复功能小鼠模型的证据。
Endocrinology. 2010 Jul;151(7):3386-95. doi: 10.1210/en.2009-1334. Epub 2010 May 5.
8
Stem cell-like properties of the endometrial side population: implication in endometrial regeneration.子宫内膜侧群细胞的干细胞样特性：在子宫内膜再生中的意义。
PLoS One. 2010 Apr 28;5(4):e10387. doi: 10.1371/journal.pone.0010387.
9
The bone marrow-derived human mesenchymal stem cell: potential progenitor of the endometrial stromal fibroblast.骨髓来源的人骨髓间充质干细胞：子宫内膜基质成纤维细胞的潜在前体细胞。
Biol Reprod. 2010 Jun;82(6):1076-87. doi: 10.1095/biolreprod.109.082867. Epub 2010 Feb 10.
10
Coexistence of quiescent and active adult stem cells in mammals.哺乳动物静止和活跃的成年干细胞共存。
Science. 2010 Jan 29;327(5965):542-5. doi: 10.1126/science.1180794.
Zotero 插件