奥地利产碳青霉烯酶肺炎克雷伯菌的医院感染爆发。
Nosocomial outbreak of Klebsiella pneumoniae carbapenemase-producing Klebsiella oxytoca in Austria.
机构信息
Section of Infectious Diseases, Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
出版信息
Antimicrob Agents Chemother. 2012 Apr;56(4):2158-61. doi: 10.1128/AAC.05440-11. Epub 2012 Jan 30.
Abstract
To date, no outbreak of carbapenemase-producing bacteria has been reported for Austria. While outbreaks of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae have been increasingly reported, no outbreak caused by KPC-producing Klebsiella oxytoca has been described yet, to the best of our knowledge. We report an outbreak of KPC-producing K. oxytoca. In 5 months, 31 KPC-producing Klebsiella oxytoca strains were isolated from five patients. All patients were admitted to the same medical intensive care unit in Austria.
摘要
迄今为止，奥地利尚未报告碳青霉烯酶产生细菌的爆发。虽然产肺炎克雷伯菌碳青霉烯酶 (KPC) 的肺炎克雷伯菌的爆发越来越多，但据我们所知，尚未描述产 KPC 的产酸克雷伯菌引起的爆发。我们报告了一起产 KPC 的产酸克雷伯菌爆发。在 5 个月内，从奥地利同一家医疗重症监护病房的五名患者中分离出 31 株产 KPC 的产酸克雷伯菌。
相似文献
1
Nosocomial outbreak of Klebsiella pneumoniae carbapenemase-producing Klebsiella oxytoca in Austria.奥地利产碳青霉烯酶肺炎克雷伯菌的医院感染爆发。
Antimicrob Agents Chemother. 2012 Apr;56(4):2158-61. doi: 10.1128/AAC.05440-11. Epub 2012 Jan 30.
2
Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.肾移植病房产OXY-2的产酸克雷伯菌暴发。
J Clin Microbiol. 2008 Jun;46(6):2099-101. doi: 10.1128/JCM.00194-08. Epub 2008 Apr 16.
3
Clonal replacement of epidemic KPC-producing Klebsiella pneumoniae in a hospital in China.中国一家医院中流行的产KPC肺炎克雷伯菌的克隆替代现象
BMC Infect Dis. 2017 May 23;17(1):363. doi: 10.1186/s12879-017-2467-9.
4
An outbreak of infection due to beta-Lactamase Klebsiella pneumoniae Carbapenemase 2-producing K. pneumoniae in a Greek University Hospital: molecular characterization, epidemiology, and outcomes.希腊某大学医院产碳青霉烯酶肺炎克雷伯菌β-内酰胺酶 2 的肺炎克雷伯菌感染暴发：分子特征、流行病学和结局。
Clin Infect Dis. 2010 Feb 1;50(3):364-73. doi: 10.1086/649865.
5
A nosocomial outbreak of KPC-2-producing Klebsiella pneumoniae in a Chinese hospital: dissemination of ST11 and emergence of ST37, ST392 and ST395.一家中国医院中产 KPC-2 的肺炎克雷伯菌的医院感染爆发：ST11 的传播和 ST37、ST392 和 ST395 的出现。
Clin Microbiol Infect. 2013 Nov;19(11):E509-15. doi: 10.1111/1469-0691.12275. Epub 2013 Jul 10.
6
Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.从纽约市一家医院分离出的克雷伯氏菌菌株质粒上 blaKPC 碳青霉烯酶基因周围转座酶区域的基因组织。
Antimicrob Agents Chemother. 2009 May;53(5):1998-2004. doi: 10.1128/AAC.01355-08. Epub 2009 Mar 2.
7
Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward.污染的洗手池作为血液科病房产KPC-2肺炎克雷伯菌克隆暴发的源头。
Antimicrob Agents Chemother. 2015 Jan;59(1):714-6. doi: 10.1128/AAC.04306-14. Epub 2014 Oct 27.
8
Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system.产 blaKPC 肺炎克雷伯菌在长期急性护理医院的出现：对我们医疗体系的新挑战。
J Antimicrob Chemother. 2009 Nov;64(5):1102-10. doi: 10.1093/jac/dkp327. Epub 2009 Sep 9.
9
Outbreak of extended-spectrum β-lactamase-producing Klebsiella oxytoca infections associated with contaminated handwashing sinks(1).产超广谱β-内酰胺酶的氧化葡萄糖酸克雷伯菌感染暴发与污染的洗手池有关(1)。
Emerg Infect Dis. 2012 Aug;18(8):1242-7. doi: 10.3201/eid1808.111268.
10
First outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in Germany.德国首次爆发产碳青霉烯酶肺炎克雷伯菌（KPC）的肺炎克雷伯菌。
Eur J Clin Microbiol Infect Dis. 2010 May;29(5):563-70. doi: 10.1007/s10096-010-0896-0. Epub 2010 Mar 7.
引用本文的文献
1
Global Epidemiology and Antimicrobial Resistance of Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Gram-Negative Clinical Isolates: A Review.产肺炎克雷伯菌碳青霉烯酶（KPC）革兰阴性临床分离株的全球流行病学及抗菌药物耐药性：综述
Microorganisms. 2025 Jul 19;13(7):1697. doi: 10.3390/microorganisms13071697.
2
Epidemiology and antimicrobial resistance of toxin-producing clinical isolates from children admitted to the oncology chemotherapy center in Mofid Children's Hospital in Tehran, Iran: A cross-sectional study.伊朗德黑兰莫菲德儿童医院肿瘤化疗中心收治儿童产毒素临床分离株的流行病学及抗菌药物耐药性：一项横断面研究
Health Sci Rep. 2024 Jul 31;7(8):e2275. doi: 10.1002/hsr2.2275. eCollection 2024 Aug.
3
Core genome multilocus sequence typing (cgMLST) applicable to the monophyletic species complex.核心基因组多位点序列分型 (cgMLST) 适用于单系种复合体。
J Clin Microbiol. 2024 Jun 12;62(6):e0172523. doi: 10.1128/jcm.01725-23. Epub 2024 May 23.
4
Resistome and Genome Analysis of an Extensively Drug-Resistant KMIB106: Characterization of a Novel KPC Plasmid pB106-1 and a Novel Cointegrate Plasmid pB106-IMP Harboring and .一株广泛耐药肺炎克雷伯菌KMIB106的耐药组与基因组分析：新型KPC质粒pB106-1和携带及的新型整合质粒pB106-IMP的特征分析
Antibiotics (Basel). 2023 Sep 20;12(9):1463. doi: 10.3390/antibiotics12091463.
5
Genomic characterization of carbapenem-resistant complex in China: a multi-center study.中国碳青霉烯类耐药菌复合体的基因组特征：一项多中心研究
Front Microbiol. 2023 Jul 3;14:1153781. doi: 10.3389/fmicb.2023.1153781. eCollection 2023.
6
Zinc-Based Nanoparticles Reduce Bacterial Biofilm Formation.锌基纳米颗粒可减少细菌生物膜形成。
Microbiol Spectr. 2023 Feb 28;11(2):e0483122. doi: 10.1128/spectrum.04831-22.
7
Klebsiella oxytoca Complex: Update on Taxonomy, Antimicrobial Resistance, and Virulence.产酸克雷伯菌复合体：分类学、抗菌耐药性和毒力的最新研究进展。
Clin Microbiol Rev. 2022 Jan 19;35(1):e0000621. doi: 10.1128/CMR.00006-21. Epub 2021 Dec 1.
8
Exploring the Global Spread of Klebsiella grimontii Isolates Possessing and .探索携带 和 的 肺炎克雷伯菌分离株的全球传播
Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0072421. doi: 10.1128/AAC.00724-21.
9
Economic burden of inpatients infected with Klebsiella pneumoniae carbapenemase.携带碳青霉烯酶肺炎克雷伯菌感染住院患者的经济负担
Einstein (Sao Paulo). 2019 May 16;17(4):eGS4444. doi: 10.31744/einstein_journal/2019GS4444.
10
Performance of the FilmArray Blood culture identification panel in positive blood culture bottles and cerebrospinal fluid for the diagnosis of sepsis and meningitis.FilmArray血培养鉴定板在阳性血培养瓶和脑脊液中用于诊断败血症和脑膜炎的性能。
GMS Infect Dis. 2016 Sep 9;4:Doc06. doi: 10.3205/id000024. eCollection 2016.
本文引用的文献
1
First report of Klebsiella oxytoca strain coproducing KPC-2 and IMP-8 carbapenemases.首次报道产 KPC-2 和 IMP-8 碳青霉烯酶的解鸟氨酸克雷伯菌。
Antimicrob Agents Chemother. 2011 Jun;55(6):2937-41. doi: 10.1128/AAC.01670-10. Epub 2011 Mar 21.
2
Outbreak of Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae with high qnr prevalence in a Chinese hospital.中国某医院产碳青霉烯酶肺炎克雷伯菌的爆发，其中高比例携带 qnr 基因。
J Med Microbiol. 2011 Jul;60(Pt 7):977-982. doi: 10.1099/jmm.0.015826-0. Epub 2011 Mar 10.
3
New Delhi metallo-β-lactamase and multidrug resistance: a global SOS?新德里金属β-内酰胺酶与多重耐药性：全球发出的紧急求救信号？
Clin Infect Dis. 2011 Feb 15;52(4):485-7. doi: 10.1093/cid/ciq179.
4
Plasmid-mediated carbapenem-hydrolysing β-lactamase KPC-2 in a Klebsiella pneumoniae isolate from Switzerland.瑞士一株肺炎克雷伯菌分离株中质粒介导的碳青霉烯水解β-内酰胺酶KPC-2
J Antimicrob Chemother. 2011 Mar;66(3):675-6. doi: 10.1093/jac/dkq499. Epub 2010 Dec 29.
5
Carbapenemases in enterobacteria, Hong Kong, China, 2009.2009年中国香港肠杆菌科细菌中的碳青霉烯酶
Emerg Infect Dis. 2011 Jan;17(1):130-2. doi: 10.3201/eid1701.101443.
6
Emergence of New Delhi metallo-β-lactamase, Austria.新德里金属β-内酰胺酶在奥地利的出现
Emerg Infect Dis. 2011 Jan;17(1):129-30. doi: 10.3201/eid1701.101331.
7
Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts.欧洲耐碳青霉烯肠杆菌科细菌：国家专家会议的结论。
Euro Surveill. 2010 Nov 18;15(46):19711. doi: 10.2807/ese.15.46.19711-en.
8
Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan.密歇根州底特律大都市爆发多粘菌素耐药、碳青霉烯类耐药肺炎克雷伯菌。
Antimicrob Agents Chemother. 2011 Feb;55(2):593-9. doi: 10.1128/AAC.01020-10. Epub 2010 Nov 29.
9
Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene.产生 blaKPC-2 基因的产超广谱β-内酰胺酶肺炎克雷伯菌的全球多样性。
Emerg Infect Dis. 2010 Sep;16(9):1349-56. doi: 10.3201/eid1609.091389.
10
Emergence of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains and spread of an isolate of sequence type 258 in the neuro-rehabilitation unit of an Italian hospital.产KPC-2碳青霉烯酶肺炎克雷伯菌菌株的出现以及一株序列型258分离株在意大利一家医院神经康复科的传播。
J Chemother. 2010 Jun;22(3):212-4. doi: 10.1179/joc.2010.22.3.212.
Zotero 插件