Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Antimicrob Agents Chemother. 2012 Apr;56(4):2132-4. doi: 10.1128/AAC.05530-11. Epub 2012 Jan 30.
We studied a clinical isolate of Salmonella enterica serotype Enteritidis showing resistance to oxyiminocephalosporins. PCR analysis confirmed the presence of bla(CTX-M-14) linked to IS903 in a 95-kb IncI1 conjugative plasmid. Such a plasmid is maintained on account of the presence of a pndAC addiction system. Multilocus sequence typing (MLST) analysis indicated that the strain belongs to ST11. This is the first report of bla(CTX-M-14) in Salmonella Enteritidis of human origin in South America.
我们研究了一株对氧亚氨基头孢菌素具有耐药性的肠炎沙门氏菌临床分离株。PCR 分析证实,bla(CTX-M-14) 基因与位于 95kb IncI1 可接合质粒上的 IS903 相连。这种质粒的存在是由于 pndAC 成瘾系统的存在。多位点序列分型 (MLST) 分析表明,该菌株属于 ST11。这是南美地区首次报道人源肠炎沙门氏菌携带 bla(CTX-M-14)。