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[原发性腹膜粒细胞肉瘤:一例报告及文献复习]

[Primary granulocytic sarcoma of the peritoneum: a case report and literature review].

作者信息

Eddou Hicham, El Bouzidi Abderrahmane, Valero Elodie, Helissey Carole, Malfuson Jean Valere, De Revel Thierry, Doghmi Kamal, Mikdame Mohammed

机构信息

Service d'hématologie, Hôpital militaire d'instruction des Armées Percy, Clamart.

出版信息

Ann Biol Clin (Paris). 2012 Jan-Feb;70(1):93-7. doi: 10.1684/abc.2011.0656.

Abstract

Granulocytic sarcoma is a rare tumor composed of immature granulocytic cells. Prognosis is poor. The periosteum is preferentially involved. A peritoneum localization is unusual. We report the case of a 20 years old man without particular previous pathologies, which brutally presented an ascitic syndrome in a context of health impairment state. The laparoscopy showes many white nodules on all the peritoneum. The histologic examination of one of these nodules showed granulocytic sarcoma. The blood and bone marrow cell count are without any anomaly. The treatment consisted of a standard acute myeloid leukaemia's chemotherapy with very good evolution. The rarity of peritoneal chloroma causes a diagnostic problem, especially in the absence of hematologic abnormalities. It must be mentioned in the presence of peritoneal nodules even if the blood count and bone marrow are normal.

摘要

粒细胞肉瘤是一种由未成熟粒细胞组成的罕见肿瘤。预后较差。骨膜是其优先累及部位。腹膜定位并不常见。我们报告一例20岁男性病例,该患者既往无特殊病史,在健康受损状态下突然出现腹水综合征。腹腔镜检查显示整个腹膜有许多白色结节。其中一个结节的组织学检查显示为粒细胞肉瘤。血液和骨髓细胞计数无任何异常。治疗采用标准的急性髓系白血病化疗,病情进展良好。腹膜绿色瘤的罕见性导致诊断困难,尤其是在没有血液学异常的情况下。即使血常规和骨髓检查正常,在出现腹膜结节时也必须考虑到该病。

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