Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Indian J Pediatr. 2012 Oct;79(10):1323-7. doi: 10.1007/s12098-011-0677-5.
To estimate the prevalence of Human metapneumovirus (hPMV), its epidemiological and clinical features in infants and children with respiratory infections, attending outpatients' clinic of Mansoura University Children Hospital (MUCH).
After taking history, clinical examination and appropriate investigations, nasopharyngeal aspirates were collected from 600 infants and children with symptoms and signs of respiratory infections. Samples were examined by RT-PCR for hMPV.
The overall prevalence of hMPV infection among studied patients was 8% (95% = 6.1-10.4). The rate was significantly higher among children aged 2-24 mo compared to other age groups (11.9% vs. 3.7% and 4.0% for 2-24, 25-60, 61-108 mo respectively). Also it was significantly higher among females than males (12.6% vs. 6.6%). Cough, wheezing, rhinorrhea, fever and chest wall retraction were the most frequent presentations (81.2%, 68.8%, 66.7%, 64.6% and 56.3%; respectively). Antibiotics, bronchodilators and oxygen administration were the most common treatments offered (60.4%, 31.2% and 27.1%; respectively).
hMPV is an emerging cause of acute respiratory infection in Mansoura University Children Hospital (MUCH), and may have a significant clinical impact on infants and children and thus, must be considered in etiological diagnosis.
评估人偏肺病毒（hMPV）在曼苏拉大学儿童医院（MUCH）门诊呼吸道感染患儿中的流行率及其流行病学和临床特征。
对 600 例有呼吸道感染症状和体征的婴幼儿进行病史采集、临床检查和适当的检查后，采集鼻咽抽吸物。通过 RT-PCR 检测 hMPV。
在所研究的患者中，hMPV 感染的总患病率为 8%（95%CI=6.1-10.4）。2-24 月龄儿童的感染率明显高于其他年龄组（11.9%比 2-24、25-60、61-108 月龄的 3.7%和 4.0%）。女性的感染率也明显高于男性（12.6%比 6.6%）。咳嗽、喘息、流涕、发热和胸廓凹陷是最常见的表现（81.2%、68.8%、66.7%、64.6%和 56.3%）。最常见的治疗方法是抗生素、支气管扩张剂和吸氧（60.4%、31.2%和 27.1%）。
hMPV 是曼苏拉大学儿童医院（MUCH）急性呼吸道感染的一种新兴病因，可能对婴幼儿有重大的临床影响，因此在病因诊断中必须考虑。
