经皮肤吸收导致严重利多卡因中毒。
Severe lidocaine intoxication by cutaneous absorption.
作者信息
Lie R L, Vermeer B J, Edelbroek P M
机构信息
Department of Internal Medicine, University Hospital Leiden, The Netherlands.
出版信息
J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):1026-8. doi: 10.1016/0190-9622(90)70329-g.
PMID:2229534
Abstract
A severe lidocaine intoxication by cutaneous absorption is described. Data are presented to show a significant absorption of lidocaine through diseased skin when lidocaine cream is used as a local anesthetic. Awareness of this route of intoxication might be important in patients in whom neurologic or psychiatric symptoms develop while large amounts of lidocaine cream are being used.
摘要
本文描述了一例因皮肤吸收导致的严重利多卡因中毒病例。数据表明，当利多卡因乳膏用作局部麻醉剂时，利多卡因可通过病变皮肤大量吸收。对于在使用大量利多卡因乳膏时出现神经或精神症状的患者，认识到这种中毒途径可能很重要。
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