Beaulé Paul E, Kim Young-Jo, Rakhra Kawan S, Stelzeneder David, Brown Thomas D
Division of Orthopaedic Surgery, University of Ottawa, Ottawa, Ontario, Canada.
Instr Course Lect. 2012;61:253-62.
High-resolution MRI for cartilage mapping is a rapidly evolving field that is contributing to a better understanding of osteoarthritis. The basic science of cartilage imaging uses different modalities (such as T1rho, T2 mapping, delayed gadolinium-enhanced MRI of cartilage) and has clinical applicability for treating hip disorders in the young adult. These imaging techniques rely on biomarkers to quantify early cartilage degeneration. The common biomarkers are proteoglycan concentration and collagen integrity. Imaging the hip presents unique challenges because of its sphericity, the close apposition of the two cartilage layers, and the limitations in using surface coils.
用于软骨成像的高分辨率磁共振成像(MRI)是一个快速发展的领域,有助于更好地理解骨关节炎。软骨成像的基础科学使用不同的模态(如T1rho、T2成像、延迟钆增强软骨MRI),并且在治疗年轻成年人的髋关节疾病方面具有临床适用性。这些成像技术依靠生物标志物来量化早期软骨退变。常见的生物标志物是蛋白聚糖浓度和胶原蛋白完整性。由于髋关节的球形结构、两层软骨的紧密贴合以及使用表面线圈的局限性,对髋关节进行成像存在独特的挑战。