Watkinson S C, Eastwood D C
Department of Plant Sciences, University of Oxford, Oxford, United Kingdom.
Adv Appl Microbiol. 2012;78:121-49. doi: 10.1016/B978-0-12-394805-2.00005-1.
Serpula lacrymans, the causative agent of dry rot timber decay in buildings, is a Basidiomycete fungus in the Boletales clade. It owes its destructiveness to a uniquely well-developed capacity to colonize by rapid mycelial spread from sites of initial spore infection, coupled with aggressive degradation of wood cellulose. Genomic methods have recently elucidated the evolution and enzymic repertoire of the fungus, suggesting that it has a distinctive mode of brown rot wood decay. Using novel methods to image nutrient translocation, its mycelium has been modeled as a highly responsive resource-supply network. Dry rot is preventable by keeping timber dry. However, in established outbreaks, further mycelial spread can be arrested by inhibitors of translocation.
干腐菌（Serpula lacrymans）是建筑物中导致木材干腐的病原体，属于牛肝菌目中的担子菌真菌。它具有独特且高度发达的能力，能从初始孢子感染部位通过快速的菌丝体扩散进行定殖，并对木材纤维素进行强力降解，从而具有很强的破坏性。基因组学方法最近阐明了该真菌的进化过程和酶谱，表明它具有独特的褐腐木材腐朽模式。利用新的营养物质转运成像方法，其菌丝体被模拟为一个高度响应的资源供应网络。保持木材干燥可预防干腐。然而，在已发生的疫情中，转运抑制剂可阻止菌丝体的进一步扩散。
