• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Yet another role for natural killer cells: cytotoxicity in immune regulation and viral persistence.

作者信息

Biron Christine A

机构信息

Department of Molecular Microbiology and Immunology, Division of Biology and Medicine and The Warren Alpert School of Medicine, Brown University, Providence, RI 02912, USA.

出版信息

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1814-5. doi: 10.1073/pnas.1120528109. Epub 2012 Jan 31.

DOI:10.1073/pnas.1120528109
PMID:22308452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3277572/
Abstract
摘要

相似文献

1
Yet another role for natural killer cells: cytotoxicity in immune regulation and viral persistence.自然杀伤细胞的另一个作用：免疫调节和病毒持续存在中的细胞毒性。
Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1814-5. doi: 10.1073/pnas.1120528109. Epub 2012 Jan 31.
2
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.自然杀伤细胞的激活通过限制 CD8+T 细胞免疫来增强免疫病理并促进慢性感染。
Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1210-5. doi: 10.1073/pnas.1118834109. Epub 2011 Dec 13.
3
Therapeutic depletion of natural killer cells controls persistent infection.自然杀伤细胞的治疗性清除可控制持续性感染。
J Virol. 2014 Feb;88(4):1953-60. doi: 10.1128/JVI.03002-13. Epub 2013 Nov 27.
4
Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin.在缺乏丝甘蛋白聚糖的小鼠中，CD8 + T细胞对淋巴细胞性脉络丛脑膜炎病毒感染的反应延迟收缩。
J Immunol. 2008 Jul 15;181(2):1043-51. doi: 10.4049/jimmunol.181.2.1043.
5
NKG2D stimulation of CD8 T cells during priming promotes their capacity to produce cytokines in response to viral infection in mice.在初始阶段刺激 CD8 T 细胞的 NKG2D 可促进其在感染病毒时产生细胞因子的能力。
Eur J Immunol. 2017 Jul;47(7):1123-1135. doi: 10.1002/eji.201646805. Epub 2017 May 2.
6
Taking the brake off T cells in chronic viral infection.解除慢性病毒感染中T细胞的制动。
Nat Med. 2006 Mar;12(3):276-7. doi: 10.1038/nm0306-276.
7
Generation of cellular immune memory and B-cell immunity is impaired by natural killer cells.自然杀伤细胞会损害细胞免疫记忆和B细胞免疫的产生。
Nat Commun. 2015 Feb 27;6:6375. doi: 10.1038/ncomms7375.
8
Distinct CD8 T cell functions mediate susceptibility to histoplasmosis during chronic viral infection.不同的CD8 T细胞功能介导慢性病毒感染期间对组织胞浆菌病的易感性。
J Immunol. 2001 Oct 15;167(8):4566-73. doi: 10.4049/jimmunol.167.8.4566.
9
Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon.病毒诱导的短暂性免疫抑制和 I 型干扰素对 T 细胞增殖的抑制作用。
J Virol. 2011 Jun;85(12):5929-39. doi: 10.1128/JVI.02516-10. Epub 2011 Apr 6.
10
The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus.CD8 + T细胞对淋巴细胞性脉络丛脑膜炎病毒的反应涉及L抗原：揭示一种旧病毒的新把戏。
J Virol. 2007 May;81(10):4928-40. doi: 10.1128/JVI.02632-06. Epub 2007 Feb 28.

引用本文的文献

1
Biomarkers in Detection of Hepatitis C Virus Infection.丙型肝炎病毒感染检测中的生物标志物
Pathogens. 2024 Apr 17;13(4):331. doi: 10.3390/pathogens13040331.
2
Cytotoxicity of Donor Natural Killer Cells to Allo-Reactive T Cells Are Related With Acute Graft-vs.-Host-Disease Following Allogeneic Stem Cell Transplantation.供者自然杀伤细胞对同种反应性 T 细胞的细胞毒性与异基因造血干细胞移植后急性移植物抗宿主病有关。
Front Immunol. 2020 Jul 31;11:1534. doi: 10.3389/fimmu.2020.01534. eCollection 2020.
3
Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.白细胞介素-15 复合物治疗通过诱导产生白细胞介素-10 的自然杀伤细胞来保护小鼠免受脑型疟疾。
Immunity. 2018 Apr 17;48(4):760-772.e4. doi: 10.1016/j.immuni.2018.03.012. Epub 2018 Apr 3.
4
Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment.接受来迪派韦/索磷布韦治疗后自然杀伤细胞的早期和晚期变化
Hepatol Commun. 2018 Mar 1;2(4):364-375. doi: 10.1002/hep4.1166. eCollection 2018 Apr.
5
Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems.评估依非韦伦固体药物纳米颗粒与人免疫和血液系统的相互作用。
J Nanobiotechnology. 2018 Mar 15;16(1):22. doi: 10.1186/s12951-018-0349-y.
6
Marek's disease in chickens: a review with focus on immunology.鸡马立克氏病：一篇聚焦免疫学的综述
Vet Res. 2016 Nov 28;47(1):119. doi: 10.1186/s13567-016-0404-3.
7
Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation.经许可的自然杀伤细胞介导的急性病毒控制使初始CD8 + T细胞依赖CD27共刺激。
J Immunol. 2016 Dec 1;197(11):4360-4370. doi: 10.4049/jimmunol.1601049. Epub 2016 Oct 24.
8
Intrahepatic regulation of antiviral T cell responses at initial stages of viral infection.病毒感染初始阶段肝内抗病毒T细胞反应的调节
Int Immunopharmacol. 2016 Oct;39:106-112. doi: 10.1016/j.intimp.2016.07.021. Epub 2016 Jul 25.
9
Intrinsic Contribution of Perforin to NK-Cell Homeostasis during Mouse Cytomegalovirus Infection.穿孔素在小鼠巨细胞病毒感染期间对自然杀伤细胞稳态的内在贡献。
Front Immunol. 2016 Apr 6;7:133. doi: 10.3389/fimmu.2016.00133. eCollection 2016.
10
Cytokine-Mediated Activation of NK Cells during Viral Infection.病毒感染期间细胞因子介导的自然杀伤细胞激活
J Virol. 2015 Aug;89(15):7922-31. doi: 10.1128/JVI.00199-15. Epub 2015 May 20.

本文引用的文献

1
Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience.自然杀伤细胞在病毒感染期间的反应：经验对先天免疫的灵活性和调节。
Curr Opin Virol. 2011 Dec;1(6):497-512. doi: 10.1016/j.coviro.2011.10.017.
2
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.自然杀伤细胞的激活通过限制 CD8+T 细胞免疫来增强免疫病理并促进慢性感染。
Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1210-5. doi: 10.1073/pnas.1118834109. Epub 2011 Dec 13.
3
The NK cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8(+) T-cell response.NK 细胞对小鼠巨细胞病毒感染的反应影响早期 CD8(+) T 细胞反应的水平和动力学。
J Virol. 2012 Feb;86(4):2165-75. doi: 10.1128/JVI.06042-11. Epub 2011 Dec 7.
4
Natural killer cells act as rheostats modulating antiviral T cells.自然杀伤细胞充当调节抗病毒 T 细胞的变阻器。
Nature. 2011 Nov 20;481(7381):394-8. doi: 10.1038/nature10624.
5
Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses.前沿：在缺乏自然杀伤细胞的情况下，CD8+ T 细胞的初始激活可导致增强的记忆应答。
J Immunol. 2011 Mar 15;186(6):3304-8. doi: 10.4049/jimmunol.1004122. Epub 2011 Feb 9.
6
Innate immunity defines the capacity of antiviral T cells to limit persistent infection.先天免疫定义了抗病毒 T 细胞限制持续性感染的能力。
J Exp Med. 2010 Jun 7;207(6):1333-43. doi: 10.1084/jem.20091193. Epub 2010 May 31.
7
NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses.自然杀伤细胞介导的靶细胞杀伤可触发强烈的抗原特异性T细胞介导的免疫反应和体液免疫反应。
Blood. 2009 Jun 25;113(26):6593-602. doi: 10.1182/blood-2009-01-201467. Epub 2009 Apr 30.
8
Natural killer cells promote early CD8 T cell responses against cytomegalovirus.自然杀伤细胞促进针对巨细胞病毒的早期CD8 T细胞反应。
PLoS Pathog. 2007 Aug 24;3(8):e123. doi: 10.1371/journal.ppat.0030123.
9
Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis.抗原激活的人类T淋巴细胞通过ATM/ATR依赖机制表达细胞表面NKG2D配体，并变得易受自体NK细胞裂解。
Blood. 2007 Jul 15;110(2):606-15. doi: 10.1182/blood-2006-10-052720. Epub 2007 Apr 3.
10
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.DNA损伤通路调节NKG2D受体的固有免疫系统配体。
Nature. 2005 Aug 25;436(7054):1186-90. doi: 10.1038/nature03884. Epub 2005 Jul 3.