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口疮病毒和心病毒RNA中聚C序列的顺序及位置

Sequence and location of the poly C tract in aphtho- and cardiovirus RNA.

作者信息

Black D N, Stephenson P, Rowlands D J, Brown F

出版信息

Nucleic Acids Res. 1979 Jun 11;6(7):2381-90. doi: 10.1093/nar/6.7.2381.

DOI:10.1093/nar/6.7.2381
PMID:223128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC327860/
Abstract

The poly C tract in the RNA of the aphtho- and cardio viruses has been examined in several isolates of foot-and-mouth disease virus (FMDV) and encephalomyocarditis (EMC) virus. The length of the tract is variable, containing 100 to 170 bases in the FMDV isolates and 80 to 250 bases in the EMC virus isolates. Each poly C tract contains c. 10% A and U residues, located at the 5' end, i.e. most of the tract is a continuous run of C residues. The position of the tract on the genome was the same in each of the FMDV isolates, about 400 bases from the 5' end, whereas in the EMC virus isolates it was about 150 bases from the 5' end.

摘要

已对口蹄疫病毒(FMDV)和脑心肌炎(EMC)病毒的多个分离株中的口疮病毒和心病毒RNA中的聚C序列进行了研究。该序列的长度是可变的,在FMDV分离株中含有100至170个碱基,在EMC病毒分离株中含有80至250个碱基。每个聚C序列含有约10%的A和U残基,位于5'端,即该序列的大部分是连续的C残基。该序列在基因组上的位置在每个FMDV分离株中是相同的,距5'端约400个碱基,而在EMC病毒分离株中距5'端约150个碱基。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/aaddab71befd/nar00448-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/d88909ba4ef3/nar00448-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/ce99906a6137/nar00448-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/aaddab71befd/nar00448-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/d88909ba4ef3/nar00448-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/ce99906a6137/nar00448-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a007/327860/aaddab71befd/nar00448-0015-a.jpg

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1
Sequence and location of the poly C tract in aphtho- and cardiovirus RNA.口疮病毒和心病毒RNA中聚C序列的顺序及位置
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本文引用的文献

1
PURIFICATION OF RADIOACTIVE FOOT-AND-MOUTH DISEASE VIRUS.放射性口蹄疫病毒的纯化
Nature. 1963 Sep 21;199:1168-70. doi: 10.1038/1991168a0.
2
Poly(C) in animal viral RNAs.动物病毒RNA中的聚胞嘧啶
Nature. 1974 Sep 27;251(5473):342-4. doi: 10.1038/251342a0.
3
Presence of a large poly(rC) tract within the RNA of encephalomyocarditis virus.脑心肌炎病毒RNA中存在一个大的聚(胞嘧啶)序列。
2022年在印度尼西亚检测到的口蹄疫病毒基因组序列
Microbiol Resour Announc. 2023 Feb 16;12(2):e0108122. doi: 10.1128/mra.01081-22. Epub 2023 Jan 9.
4
The long-lasting enigma of polycytidine (polyC) tract.长时持久的聚胞嘧啶(polyC)序列之谜。
PLoS Pathog. 2021 Aug 4;17(8):e1009739. doi: 10.1371/journal.ppat.1009739. eCollection 2021 Aug.
5
A universal protocol to generate consensus level genome sequences for foot-and-mouth disease virus and other positive-sense polyadenylated RNA viruses using the Illumina MiSeq.一种使用Illumina MiSeq为口蹄疫病毒和其他正链多聚腺苷酸化RNA病毒生成共识水平基因组序列的通用方案。
BMC Genomics. 2014 Sep 30;15(1):828. doi: 10.1186/1471-2164-15-828.
6
The complete nucleotide sequence of the PanAsia strain of foot-and-mouth disease virus isolated in Japan.在日本分离出的口蹄疫病毒泛亚株的完整核苷酸序列。
Virus Genes. 2002 Oct;25(2):119-25. doi: 10.1023/a:1020103700108.
7
The poly(C) region affects progression of encephalomyocarditis virus infection in Langerhans' islets but not in the myocardium.多聚胞嘧啶区域影响脑心肌炎病毒在朗格汉斯胰岛中的感染进程,但不影响其在心肌中的感染进程。
J Virol. 1997 May;71(5):4145-9. doi: 10.1128/JVI.71.5.4145-4149.1997.
8
Equine rhinovirus 1 is more closely related to foot-and-mouth disease virus than to other picornaviruses.马鼻病毒1型与口蹄疫病毒的关系比与其他小核糖核酸病毒的关系更为密切。
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):990-5. doi: 10.1073/pnas.93.3.990.
9
Genetically engineered foot-and-mouth disease viruses with poly(C) tracts of two nucleotides are virulent in mice.具有两个核苷酸的聚(C)序列的基因工程口蹄疫病毒在小鼠中具有毒性。
J Virol. 1993 Sep;67(9):5139-45. doi: 10.1128/JVI.67.9.5139-5145.1993.
10
Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts.具有短聚胞嘧啶序列的脑心肌炎病毒比其对应的 Mengovirus 更具毒性。
J Virol. 1995 Apr;69(4):2697-9. doi: 10.1128/JVI.69.4.2697-2699.1995.
Nature. 1974 Apr 19;248(5450):675-8. doi: 10.1038/248675a0.
4
New rapid gel sequencing method for RNA.用于RNA的新型快速凝胶测序方法。
Nature. 1977 Oct 27;269(5631):833-6. doi: 10.1038/269833a0.
5
An efficient mRNA-dependent translation system from reticulocyte lysates.一种来自网织红细胞裂解物的高效mRNA依赖性翻译系统。
Eur J Biochem. 1976 Aug 1;67(1):247-56. doi: 10.1111/j.1432-1033.1976.tb10656.x.
6
Identification of specific fragments containing the 5' end of poliovirus RNA after ribonuclease III digestion.核糖核酸酶III消化后含脊髓灰质炎病毒RNA 5'端的特定片段的鉴定
Nucleic Acids Res. 1978 Nov;5(11):4039-54. doi: 10.1093/nar/5.11.4039.
7
Picornaviridae: second report.小核糖核酸病毒科:第二次报告。
Intervirology. 1978;10(3):165-80. doi: 10.1159/000148981.
8
The genomic RNA of mengovirus. II: Comparative analysis of the standard and denser virions.
Virology. 1978 Apr;85(2):378-86. doi: 10.1016/0042-6822(78)90446-4.
9
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J Virol. 1978 May;26(2):335-43. doi: 10.1128/JVI.26.2.335-343.1978.
10
Biochemical analysis of a virulent and an avirulent strain of foot-and-mouth disease virus.口蹄疫病毒强毒株和无毒株的生化分析
J Gen Virol. 1977 Jan;34(1):87-105. doi: 10.1099/0022-1317-34-1-87.