Pneumology Service, Hospital de Sabadell, Corporació Parc Taulí, Sabadell 08208, Spain.
Sensors (Basel). 2010;10(1):491-500. doi: 10.3390/s100100491. Epub 2010 Jan 11.
To determine the optimal clinical reading time for the transcutaneous measurement of oxygen saturation (SpO(2)) and transcutaneous CO(2) (TcPCO(2)) in awake spontaneously breathing individuals, considering the overshoot phenomenon (transient overestimation of arterial PaCO(2)). EXPERIMENTAL SECTION: Observational study of 91 (75 men) individuals undergoing forced spirometry, measurement of SpO(2) and TcPCO(2) with the SenTec monitor every two minutes until minute 20 and arterial blood gas (ABG) analysis. Overshoot severity: (a) mild (0.1-1.9 mm Hg); (b) moderate (2-4.9 mm Hg); (c) severe: (>5 mm Hg). The mean difference was calculated for SpO(2) and TcPCO(2) and arterial values of PaCO(2) and SpO(2). The intraclass correlation coefficient (ICC) between monitor readings and blood values was calculated as a measure of agreement.
The mean age was 63.1 ± 11.8 years. Spirometric values: FVC: 75.4 ± 6.2%; FEV(1): 72.9 ± 23.9%; FEV(1)/FVC: 70 ± 15.5%. ABG: PaO(2): 82.6 ± 13.2; PaCO(2): 39.9.1 ± 4.8 mmHg; SaO(2): 95.3 ± 4.4%. Overshoot analysis: overshoot was mild in 33 (36.3%) patients, moderate in 20 (22%) and severe in nine (10%); no overshoot was observed in 29 (31%) patients. The lowest mean differences between arterial blood gas and TcPCO(2) was -0.57 mmHg at minute 10, although the highest ICC was obtained at minutes 12 and 14 (>0.8). The overshoot lost its influence after minute 12. For SpO(2), measurements were reliable at minute 2.
The optimal clinical reading measurement recommended for the ear lobe TcPCO(2) measurement ranges between minute 12 and 14. The SpO(2) measurement can be performed at minute 2.
确定清醒自主呼吸个体经皮氧饱和度(SpO₂)和经皮二氧化碳(TcPCO₂)测量的最佳临床读取时间,考虑到过冲现象(动脉 PaCO₂的短暂高估)。
对 91 名(75 名男性)接受强制肺活量测定的个体进行观察性研究,使用 SenTec 监测仪每两分钟测量一次 SpO₂和 TcPCO₂,直至第 20 分钟,并进行动脉血气(ABG)分析。过冲严重程度:(a)轻度(0.1-1.9mmHg);(b)中度(2-4.9mmHg);(c)重度:(>5mmHg)。计算 SpO₂和 TcPCO₂与动脉 PaCO₂和 SpO₂值的平均差值。监测读数与血液值之间的组内相关系数(ICC)作为一致性的衡量标准。
平均年龄为 63.1±11.8 岁。肺活量测定值:FVC:75.4±6.2%;FEV₁:72.9±23.9%;FEV₁/FVC:70±15.5%。ABG:PaO₂:82.6±13.2mmHg;PaCO₂:39.9.1±4.8mmHg;SaO₂:95.3±4.4%。过冲分析:33 例(36.3%)患者过冲为轻度,20 例(22%)为中度,9 例(10%)为重度;29 例(31%)患者无过冲。动脉血气与 TcPCO₂之间的平均差值最低为-0.57mmHg,出现在第 10 分钟,尽管第 12 分钟和第 14 分钟的 ICC 最高(>0.8)。第 12 分钟后,过冲的影响消失。对于 SpO₂,在第 2 分钟进行测量是可靠的。
推荐的经耳垂 TcPCO₂测量最佳临床读取测量时间范围在第 12 至 14 分钟之间。SpO₂的测量可以在第 2 分钟进行。