Suppr超能文献

一只狗的丙二醇中毒

Propylene glycol intoxication in a dog.

作者信息

Claus Melissa A, Jandrey Karl E, Poppenga Robert H

机构信息

Veterinary Medical Teaching Hospital, University of California Davis, Davis, CA 95616, USA.

出版信息

J Vet Emerg Crit Care (San Antonio). 2011 Dec;21(6):679-83. doi: 10.1111/j.1476-4431.2011.00688.x.

Abstract

OBJECTIVE

To describe the clinical course, treatment, and outcome of a dog with propylene glycol intoxication.

CASE SUMMARY

An adult castrated male Australian cattle dog presented to an emergency clinic for an acute onset of ataxia and disorientation after roaming a construction site unsupervised. He tested positive for ethylene glycol using a point-of-care test kit. Treatment for ethylene glycol intoxication included intermittent intravenous boluses of 20% ethanol and hemodialysis. Predialysis and postdialysis blood samples were submitted to the toxicology lab to assess for both ethylene and propylene glycol. The patient tested negative for ethylene glycol and positive for propylene glycol at 1100 mg/dL predialysis and 23 mg/dL postdialysis. The dog made a full recovery.

NEW OR UNIQUE INFORMATION PROVIDED

To the authors' knowledge, this is the first report of documented propylene glycol intoxication in a dog, as well as the first report to describe hemodialysis as treatment for propylene glycol intoxication in a dog.

摘要

目的

描述一只丙二醇中毒犬的临床病程、治疗及预后情况。

病例摘要

一只成年去势雄性澳大利亚牧牛犬在无人监管下游荡建筑工地后,因急性共济失调和定向障碍被送至一家急诊诊所。使用即时检验试剂盒检测,其乙二醇检测呈阳性。乙二醇中毒的治疗包括间歇性静脉推注20%乙醇和血液透析。透析前和透析后的血样被送至毒理学实验室,以评估乙二醇和丙二醇。透析前患者丙二醇检测呈阳性,浓度为1100mg/dL,透析后为23mg/dL,乙二醇检测呈阴性。该犬完全康复。

提供的新的或独特信息

据作者所知,这是犬丙二醇中毒的首次文献报道,也是首次描述血液透析作为犬丙二醇中毒治疗方法的报道。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验