骨质疏松症研究。II. 雌激素和氟化物对实验性骨质疏松症的影响。初步报告。
Studies on osteoporosis. II. Effect of estrogens and fluoride on experimental osteoporosis. A preliminary report.
作者信息
Robin J C, Schepart B, Calkins H, LoSasso G, Thomas C C, Ambrus J L
出版信息
Res Commun Chem Pathol Pharmacol. 1979 Mar;23(3):647-50.
PMID:223209
Abstract
Total skeletal calcium level was determined in female mice with the aid of whole body neutron activation analysis. Three months treatment with heparin produced significant osteoporosis in C3H/St(Ha) mice of 3--5 months of age. Treatment with a conjugated natural estrogen preparation (Premarin) prevented this phenomenon but high level fluoride in the drinking water failed to show preventive activity.
摘要
借助全身中子活化分析测定了雌性小鼠的总骨骼钙水平。对3至5月龄的C3H/St(Ha)小鼠进行为期三个月的肝素治疗，导致了显著的骨质疏松。使用结合型天然雌激素制剂（倍美力）进行治疗可预防此现象，但饮用水中高剂量的氟化物未显示出预防作用。
Zotero 插件