Singh Anupama, Sharma Pramod Kumar, Malviya Rishabha
Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology Bypass Road, Baghpat Crossing, NH-58, Meerut-250005, U.P., India.
Polim Med. 2011;41(4):73-80.
Polymers are the high molecular weight compounds of natural or synthetic origin, widely used in drug delivery of formulations. These polymers are further classified as hydrophilic or hydrophobic in nature. Depending upon this characteristic, polymers exhibit different release behavior in different media. This property plays an important role in the selection of polymers for controlled, sustained or immediate release formulations. The review highlights the literatures related to the research made on several polymers regarding the release kinetics which made them a novel approach for modifying the action of the particular formulation.
聚合物是天然或合成来源的高分子量化合物，广泛应用于制剂的药物递送。这些聚合物在性质上进一步分为亲水性或疏水性。根据这一特性，聚合物在不同介质中表现出不同的释放行为。这一特性在选择用于控释、缓释或速释制剂的聚合物时起着重要作用。本文综述重点介绍了有关几种聚合物释放动力学研究的文献，这些研究使聚合物成为修饰特定制剂作用的一种新方法。
