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共病使用大麻和烟草的临床相关性:系统评价。

Clinical correlates of co-occurring cannabis and tobacco use: a systematic review.

机构信息

Department of Psychiatry, Yale University School of Medicine, One Long Wharf Drive, New Haven, CT 06511, USA.

出版信息

Addiction. 2012 Aug;107(8):1404-17. doi: 10.1111/j.1360-0443.2012.03843.x. Epub 2012 Apr 17.

Abstract

AIMS

A growing literature has documented the substantial prevalence of and putative mechanisms underlying co-occurring (i.e. concurrent or simultaneous) cannabis and tobacco use. Greater understanding of the clinical correlates of co-occurring cannabis and tobacco use may suggest how intervention strategies may be refined to improve cessation outcomes and decrease the public health burden associated with cannabis and tobacco use.

METHODS

A systematic review of the literature on clinical diagnoses, psychosocial problems and outcomes associated with co-occurring cannabis and tobacco use. Twenty-eight studies compared clinical correlates in co-occurring cannabis and tobacco users versus cannabis- or tobacco-only users. These included studies of treatment-seekers in clinical trials and non-treatment-seekers in cross-sectional or longitudinal epidemiological or non-population-based surveys.

RESULTS

Sixteen studies examined clinical diagnoses, four studies examined psychosocial problems and 11 studies examined cessation outcomes in co-occurring cannabis and tobacco users (several studies examined multiple clinical correlates). Relative to cannabis use only, co-occurring cannabis and tobacco use was associated with a greater likelihood of cannabis use disorders, more psychosocial problems and poorer cannabis cessation outcomes. Relative to tobacco use only, co-occurring use did not appear to be associated consistently with a greater likelihood of tobacco use disorders, more psychosocial problems or poorer tobacco cessation outcomes.

CONCLUSIONS

Cannabis users who also smoke tobacco are more dependent on cannabis, have more psychosocial problems and have poorer cessation outcomes than those who use cannabis but not tobacco. The converse does not appear to be the case.

摘要

目的

越来越多的文献记录了同时使用大麻和烟草(即同时或同时使用)的大量流行率和潜在机制。更深入地了解同时使用大麻和烟草的临床相关性可能表明,干预策略如何得到改进,以提高戒烟效果,并减少与大麻和烟草使用相关的公共卫生负担。

方法

对同时使用大麻和烟草与单独使用大麻或烟草的临床诊断、心理社会问题和结果相关的文献进行系统回顾。28 项研究比较了同时使用大麻和烟草的使用者与单独使用大麻或烟草的使用者的临床相关性。这些研究包括临床试验中的治疗寻求者和横断面或纵向流行病学或非基于人群的调查中的非治疗寻求者。

结果

16 项研究检查了临床诊断,4 项研究检查了心理社会问题,11 项研究检查了同时使用大麻和烟草的使用者的戒烟结果(一些研究检查了多个临床相关性)。与单独使用大麻相比,同时使用大麻和烟草与大麻使用障碍的可能性更大、更多的心理社会问题和更差的大麻戒烟结果相关。与单独使用烟草相比,同时使用似乎并不总是与烟草使用障碍的可能性更大、更多的心理社会问题或更差的烟草戒烟结果相关。

结论

同时使用大麻和烟草的大麻使用者比仅使用大麻的使用者更依赖大麻,有更多的心理社会问题,戒烟效果更差。反之则不然。

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