Laboratorium für Organische Chemie, ETH Zürich, Switzerland.
Angew Chem Int Ed Engl. 2012 Apr 2;51(14):3474-7. doi: 10.1002/anie.201109175. Epub 2012 Feb 17.
Revised version: the first total synthesis of indoxamycin B leads to a stereochemical reassignment of the natural product. The synthetic route features an efficient carboannulation sequence to rapidly access the dihydroindenone system. Moreover, a series of Au(I)-catalyzed transformations served in the construction of the sterically congested core framework.
吲哚霉素 B 的首次全合成导致天然产物的立体化学重新分配。该合成路线的特点是高效的碳环化序列，可快速进入二氢茚酮系统。此外，一系列 Au(I)-催化转化在构建空间位阻核心骨架中发挥了作用。
