Medical Department, Garcia de Orta Hospital, Almada, Portugal.
Ann Hepatol. 2012 Mar-Apr;11(2):265-7.
The present report describes a 63-year-old female who presented with fulminant hepatic failure requiring liver transplantation caused by a weight loss dietary supplement containing conjugated linoleic acid (CLA). Thorough investigation, including liver biopsy, revealed no other cause of hepatotoxicity. In the last few years, a considerable number of reports have been published on toxic hepatitis, associated with non-conventional products, attributed with weight-reducing properties. We emphasize the importance of taking a cautious approach when consuming herbal supplements for the purpose of weight loss, as all that is "natural" may not always be healthy. Only one report of CLA-induced toxic hepatitis is related in the medical literature.
本报告描述了一位 63 岁女性，因服用含有共轭亚油酸（CLA）的减肥膳食补充剂而导致暴发性肝衰竭，需要进行肝移植。彻底的调查，包括肝活检，没有发现其他导致肝毒性的原因。在过去的几年中，已经发表了相当数量的报告，涉及与非传统产品相关的毒性肝炎，这些产品具有减肥特性。我们强调在为减肥而服用草药补充剂时要谨慎，因为并非所有“天然”的东西都是健康的。在医学文献中仅报道过一例与 CLA 相关的中毒性肝炎。
