Koregol Arati C, More Shobha P, Nainegali Sangamesh, Kalburgi Nagaraj, Verma Siddharth
Department of Periodontics, PMNM Dental College and Hospital, Bagalkot, Karnataka, India.
Contemp Clin Dent. 2011 Oct;2(4):278-82. doi: 10.4103/0976-237X.91788.
Gingival crevicular fluid (GCF) is regarded as a promising medium for detection of markers of periodontal disease activity. Very few investigators have examined concentration of electrolytes in GCF, but most results are not in agreement to one another. This study was undertaken with an objective of quantitative estimation of sodium, potassium and calcium concentrations of GCF in gingivitis and periodontitis, to find the reliability of these ions as diagnostic markers and to analyze the relation of these ions to one another. This will indicate stage of disease activity which helps in early diagnosis, prevention and treatment of periodontal diseases.
The patients selected for the study included both sexes, aging from 18 to 55 years, divided into two groups: gingivitis (group I) and periodontitis (group II). Using volumetric microcapillary pipette, 5 μl GCF was collected for quantitative analysis of sodium, potassium and calcium using flame photometry.
The concentrations of sodium, potassium and calcium in GCF and their significant correlation with gingival index and pocket depth measurements reflect the clinical status of gingival and periodontal tissues.
Estimation of these electrolytes may be used as potential diagnostic markers of active disease status in periodontal tissues and to predict the effective methods of prevention and treatment.
龈沟液（GCF）被视为检测牙周疾病活动标志物的一种有前景的介质。很少有研究者检测龈沟液中的电解质浓度，且大多数结果彼此不一致。本研究旨在定量评估龈炎和牙周炎患者龈沟液中钠、钾和钙的浓度，以确定这些离子作为诊断标志物的可靠性，并分析这些离子之间的相互关系。这将有助于指示疾病活动阶段，从而有助于牙周疾病的早期诊断、预防和治疗。
本研究选取的患者年龄在18至55岁之间，男女不限，分为两组：龈炎组（I组）和牙周炎组（II组）。使用容量微毛细管移液器收集5μl龈沟液，采用火焰光度法对钠、钾和钙进行定量分析。
龈沟液中钠、钾和钙的浓度及其与牙龈指数和牙周袋深度测量值的显著相关性反映了牙龈和牙周组织的临床状况。
这些电解质的评估可作为牙周组织中疾病活动状态的潜在诊断标志物，并用于预测有效的预防和治疗方法。
