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间日疟患者微量金属异常的测定

Determination of trace metals abnormalities in patients with vivax malaria.

作者信息

Baloch S, Memon Sa, Gachal Gs, Baloch M

机构信息

Department of Zoology, University of Sindh, Jamshoro, Pakistan.

出版信息

Iran J Parasitol. 2011 Jun;6(2):54-9.

PMID:22347288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3279882/
Abstract

BACKGROUND

In the present study, blood serum level of metals were determined in malarial patients and compared with those in the normal subjects without complication using Atomic Absorption Spectrometer.

METHODS

For the determination of these metals twelve intravenous blood samples each from referred malarial patients and a group of normal subjects were collected and immediately centrifuged to obtain the supernatant liquid, serum of both the groups for analysis.

RESULTS

The blood serum levels of copper in malarial patients determined to be 2.6917 ppm, which is higher as compared to that found 2.045 in normal subjects. Whereas the blood serum levels of iron, magnesium, and zinc found 2.0708 ppm, 12.2467 ppm and 4.9017 ppm respectively in malarial patients, who are lower than those, are determined in the blood serum of normal subjects. Blood serum levels of iron, magnesium, and zinc in normal subjects found 3.950 ppm, 19.4892 ppm, and 5.242 ppm respectively.

CONCLUSION

In this study the metal content of copper, iron, magnesium and zinc in vary in malarial patients as compared those in the normal subjects. It may suggest that the decreased levels of iron, magnesium, and zinc can be maintained by giving as supplement of these metals in therapy.

摘要

背景

在本研究中,使用原子吸收光谱仪测定疟疾患者血清中的金属水平,并与无并发症的正常受试者进行比较。

方法

为了测定这些金属,从转诊的疟疾患者和一组正常受试者中分别采集12份静脉血样本,立即离心以获得上清液,即两组的血清用于分析。

结果

疟疾患者血清铜水平测定为2.6917 ppm,高于正常受试者的2.045 ppm。而疟疾患者血清中铁、镁和锌的水平分别为2.0708 ppm、12.2467 ppm和4.9017 ppm,低于正常受试者血清中的水平。正常受试者血清中铁、镁和锌的水平分别为3.950 ppm、19.4892 ppm和5.242 ppm。

结论

本研究中,疟疾患者体内铜、铁、镁和锌的金属含量与正常受试者不同。这可能表明,在治疗中补充这些金属可以维持铁、镁和锌的降低水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2509/3279882/048b873036ec/IJP-6-054-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2509/3279882/e4ed1b72702d/IJP-6-054-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2509/3279882/048b873036ec/IJP-6-054-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2509/3279882/e4ed1b72702d/IJP-6-054-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2509/3279882/048b873036ec/IJP-6-054-g002.jpg

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Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria.间日疟患者体内必需微量元素硒、锌、铜和铁的浓度及其相关急性期蛋白
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一项系统回顾和荟萃分析,旨在探讨疟疾患者和未感染对照个体之间铜水平的差异。
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Electrolyte Disturbance and the Type of Malarial Infection.电解质紊乱与疟疾感染类型
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